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README.md

@@ -117,7 +117,7 @@ CALDER_sub_domains(intermediate_data_file,
 | **contact_file_dump**                |A list of contact files in dump format, named by `chrs`. Each contact file stores the contact information of the corresponding `chr`
 | **contact_tab_dump**                | A list of contact table in dump format, named by `chrs`, stored as an R object
 | **contact_file_hic**                | A hic file generated by Juicer tools. It should contain all chromosomes in `chrs`
-| **ref_genome**                | One of 'hg19', 'hg38', 'mm9', 'mm10', 'others' (default). High quality compartment calls were generated for 'hg19' (using hic data from GSE63525), 'hg38' (using hic data from https://data.4dnucleome.org/files-processed/4DNFI1UEG1HD/), 'mm9' (using hic data from GSM3959427), 'mm10' (using hic data from http://hicfiles.s3.amazonaws.com/external/bonev/CN_mapq30.hic)
+| **ref_genome**                | One of 'hg19', 'hg38', 'mm9', 'mm10', 'others' (default). High quality compartment calls were generated for 'hg19' (using hic data from GSE63525), 'hg38' (using hic data from https://data.4dnucleome.org/files-processed/4DNFI1UEG1HD/), 'mm9' (using hic data from GSM3959427), 'mm10' (using hic data from http://hicfiles.s3.amazonaws.com/external/bonev/CN_mapq30.hic). These compartments will be used as reference compartments for optimized bin_size selection. If `ref_genome = others`, an `annotation_track` should be provided (see below) and no optimized bin_size selection will be performed 
 | **annotation_track**                | A genomic annotation track in `data.frame` or `data.table` format. This track will be used for determing the A/B compartment direction and should presumably have higher values | in A than in B compartment. Some suggested tracks can be: 
 | **contact_file_hic**                | Path to the hic xx
 | **bin_size**         | numeric, the size of a bin in consistent with the contact table