浏览代码

Update README.md

Yuanlong LIU 1 年之前
父节点
当前提交
5a8c0b07cb
共有 1 个文件被更改,包括 3 次插入2 次删除
  1. 3 2
      README.md

+ 3 - 2
README.md

@@ -13,9 +13,10 @@ CALDER is a Hi-C analysis tool that allows: (1) compute chromatin domains from w
 * Calder connects chromatin 3D organization to genomic function:
 ![Alt text](./img/CALDER_features.png "CALDER features")
 
-## A note with with respect to PC-based method
+## (A note on the performance of Calder vs PC)
+
+* Except for being able to identify non-linear sub-compartments, Calder demonstrates superior robustness over PC-based approach in identifying meaningful compartments, particularly when faced with complex chromosomal structural variations (figure on the left) and loose interaction between the p and q arms (figure on the right)
 
-* Overview of the CALDER method:
 ![Alt text](./img/Hela_chr11_and_RWPE1_chr9_pq.png "Hela_chr11_and_RWPE1_chr9_pq")