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@@ -5,12 +5,13 @@ CALDER is a Hi-C analysis tool that allows: (1) compute chromatin domains from w
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-## We added multiple new features in version 2.0:
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+## We added multiple new features in version 2.0
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-* Support for other genomes
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-* Support hic format generated by Juicer tools (https://github.com/aidenlab/juicer)
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+* Support for hg19, hg38, mm9, mm10, and other genomes
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+* Support input in hic format generated by Juicer tools (https://github.com/aidenlab/juicer)
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* Opimized resolution selection
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-*
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+* Added output in tabular txt format for downstream analysis
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+* All chromosome output aggregated into a single file
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Although compartments can change between different cell conditions, from our large scale analysis we found the overall correlation between two conditions are high. We input compartment of reference dataset. When the computed compartment has low correlation with this reference, it indicates false calling.
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Yuanlong LIU