|
@@ -78,8 +78,10 @@ remotes::install_github("CSOgroup/CALDER")
|
|
|
|
|
|
# Usage
|
|
|
|
|
|
-
|
|
|
-CALDER works on contact matrices in a three-column `dump` format as generated by the juicer dump command (https://github.com/aidenlab/juicer/wiki/Data-Extraction):
|
|
|
+CALDER contains three modules: (1) compute chromatin domains; (2) derive their hierarchical organization and obtain sub-compartments; (3) compute nested sub-domains within each compartment domain.
|
|
|
+<br>
|
|
|
+<br>
|
|
|
+CALDER works on contact matrices in a three-column `dump` format as generated by the juicer dump (or straw) command (https://github.com/aidenlab/juicer/wiki/Data-Extraction):
|
|
|
|
|
|
16050000 16050000 10106.306
|
|
|
16050000 16060000 2259.247
|
|
@@ -112,8 +114,6 @@ feature_track = data.table::as.data.table(feature_track)[, c(1:3, 6)]
|
|
|
chrY 59032416 59032456 0.92023
|
|
|
chrY 59032457 59032578 0.78875
|
|
|
|
|
|
-CALDER contains three modules: (1) compute chromatin domains; (2) derive their hierarchical organization and obtain sub-compartments; (3) compute nested sub-domains within each compartment domain.
|
|
|
-
|
|
|
### Example one: use contact matrix file in dump format as input
|
|
|
```
|
|
|
chrs = c(21:22)
|