data__sequence.inc 6.7 KB

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  1. <?php
  2. class data__sequence extends ChadoField {
  3. // --------------------------------------------------------------------------
  4. // EDITABLE STATIC CONSTANTS
  5. //
  6. // The following constants SHOULD be set for each descendent class. They are
  7. // used by the static functions to provide information to Drupal about
  8. // the field and it's default widget and formatter.
  9. // --------------------------------------------------------------------------
  10. // The default lable for this field.
  11. public static $default_label = 'Sequence';
  12. // The default description for this field.
  13. public static $description = 'A field for managing nucleotide and protein residues.';
  14. // Provide a list of instance specific settings. These can be access within
  15. // the instanceSettingsForm. When the instanceSettingsForm is submitted
  16. // then Drupal with automatically change these settings for the instnace.
  17. // It is recommended to put settings at the instance level whenever possible.
  18. // If you override this variable in a child class be sure to replicate the
  19. // term_name, term_vocab, term_accession and term_fixed keys as these are
  20. // required for all TripalFields.
  21. public static $default_instance_settings = array(
  22. // The short name for the vocabulary (e.g. shcema, SO, GO, PATO, etc.).
  23. 'term_vocabulary' => 'data',
  24. // The name of the term.
  25. 'term_name' => 'sequence',
  26. // The unique ID (i.e. accession) of the term.
  27. 'term_accession' => '2044',
  28. // Set to TRUE if the site admin is allowed to change the term
  29. // type. This will create form elements when editing the field instance
  30. // to allow the site admin to change the term settings above.
  31. 'term_fixed' => FALSE,
  32. );
  33. // The default widget for this field.
  34. public static $default_widget = 'data__sequence_widget';
  35. // The default formatter for this field.
  36. public static $default_formatter = 'data__sequence_formatter';
  37. /**
  38. * @see TripalField::load()
  39. */
  40. public function load($entity, $details = array()) {
  41. $field_name = $this->field['field_name'];
  42. $feature = $details['record'];
  43. // We don't want to get the sequence for traditionally large types. They are
  44. // too big, bog down the web browser, take longer to load and it's not
  45. // reasonable to print them on a page.
  46. if(strcmp($feature->type_id->name,'scaffold') != 0 and
  47. strcmp($feature->type_id->name,'chromosome') != 0 and
  48. strcmp($feature->type_id->name,'supercontig') != 0 and
  49. strcmp($feature->type_id->name,'pseudomolecule') != 0) {
  50. $feature = chado_expand_var($feature,'field','feature.residues');
  51. $entity->{$field_name}['und'][0]['value'] = $feature->residues;
  52. }
  53. /* // Add in sequences from alignments.
  54. $options = array(
  55. 'return_array' => 1,
  56. 'include_fk' => array(
  57. 'srcfeature_id' => array(
  58. 'type_id' => 1
  59. ),
  60. 'feature_id' => array(
  61. 'type_id' => 1
  62. ),
  63. ),
  64. );
  65. $feature = chado_expand_var($feature, 'table', 'featureloc', $options);
  66. $featureloc_sequences = $this->get_featureloc_sequences($feature->feature_id, $feature->featureloc->feature_id);
  67. // Add in the coding sequences. It's faster to provide the SQL rather than
  68. // to use chado_generate_var based on the type.
  69. $sql = "
  70. SELECT F.*
  71. FROM {feature_relationship} FR
  72. INNER JOIN {feature} F on FR.subject_id = F.feature_id
  73. INNER JOIN {cvterm} CVT on CVT.cvterm_id = F.type_id
  74. INNER JOIN {cvterm} RCVT on RCVT.cvterm_id = FR.type_id
  75. INNER JOIN {featureloc} FL on FL.feature_id = F.feature_id
  76. WHERE
  77. FR.object_id = :feature_id and
  78. CVT.name = 'CDS' and
  79. RCVT.name = 'part_of'
  80. ORDER BY FR.rank ASC
  81. ";
  82. $results = chado_query($sql, array(':feature_id' => $feature->feature_id));
  83. $coding_seq = '';
  84. while ($CDS = $results->fetchObject()) {
  85. if ($CDS->residues) {
  86. $coding_seq .= $CDS->residues;
  87. }
  88. }
  89. if ($coding_seq) {
  90. $entity->{$field_name}['und'][$num_seqs++]['value'] = array(
  91. '@type' => 'SO:0000316',
  92. 'type' => 'coding_sequence',
  93. 'label' => 'Coding sequence (CDS)',
  94. 'defline' => tripal_get_fasta_defline($feature, 'CDS', NULL, '', strlen($coding_seq)),
  95. 'residues' => $coding_seq,
  96. );
  97. }
  98. foreach($featureloc_sequences as $src => $attrs){
  99. // the $attrs array has the following keys
  100. // * id: a unique identifier combining the feature id with the cvterm id
  101. // * type: the type of sequence (e.g. mRNA, etc)
  102. // * location: the alignment location
  103. // * defline: the definition line
  104. // * formatted_seq: the formatted sequences
  105. // * featureloc: the feature object aligned to
  106. $entity->{$field_name}['und'][$num_seqs++]['value'] = array(
  107. 'residues' => $attrs['residues'],
  108. '@type' => 'SO:0000110',
  109. 'type' => 'sequence_feature',
  110. 'defline' => tripal_get_fasta_defline($feature, '', $attrs['featureloc'], 'CDS', strlen($attrs['residues'])),
  111. 'label' => 'Sequence from alignment at ' . $attrs['location'],
  112. );
  113. // check to see if this alignment has any CDS. If so, generate a CDS sequence
  114. $cds_sequence = tripal_get_feature_sequences(
  115. array(
  116. 'feature_id' => $feature->feature_id,
  117. 'parent_id' => $attrs['featureloc']->srcfeature_id->feature_id,
  118. 'name' => $feature->name,
  119. 'featureloc_id' => $attrs['featureloc']->featureloc_id,
  120. ),
  121. array(
  122. 'derive_from_parent' => 1, // CDS are in parent-child relationships so we want to use the sequence from the parent
  123. 'aggregate' => 1, // we want to combine all CDS for this feature into a single sequence
  124. 'sub_feature_types' => array('CDS'), // we're looking for CDS features
  125. 'is_html' => 0
  126. )
  127. );
  128. if (count($cds_sequence) > 0) {
  129. // the tripal_get_feature_sequences() function can return multiple sequences
  130. // if a feature is aligned to multiple places. In the case of CDSs we expect
  131. // that one mRNA is only aligned to a single location on the assembly so we
  132. // can access the CDS sequence with index 0.
  133. if ($cds_sequence[0]['residues']) {
  134. $entity->{$field_name}['und'][$num_seqs++]['value'] = array(
  135. 'residues' => $cds_sequence[0]['residues'],
  136. '@type' => 'SO:0000316',
  137. 'type' => 'coding_sequence',
  138. 'defline' => tripal_get_fasta_defline($feature, '', $attrs['featureloc'], 'CDS', $cds_sequence[0]['length']),
  139. 'label' => 'Coding sequence (CDS) from alignment at ' . $attrs['location'],
  140. );
  141. }
  142. }
  143. } */
  144. }
  145. }