tripal_feature.module 77 KB

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  1. <?php
  2. /**
  3. * @file
  4. * @todo Add file header description
  5. */
  6. /**
  7. * @defgroup tripal_feature Feature Module
  8. * @ingroup tripal_modules
  9. * @{
  10. * Provides functions for managing chado features including creating details pages for each feature
  11. * @}
  12. */
  13. require_once "includes/tripal_feature.admin.inc";
  14. require_once "includes/syncFeatures.inc";
  15. require_once "includes/indexFeatures.inc";
  16. require_once "includes/fasta_loader.inc";
  17. require_once "includes/gff_loader.inc";
  18. require_once "includes/seq_extract.inc";
  19. require_once "api/tripal_feature.api.inc";
  20. require_once "includes/tripal_feature-delete.inc";
  21. //require_once "includes/tripal_feature-secondary_tables.inc";
  22. //require_once "includes/tripal_feature-properties.inc";
  23. //require_once "includes/tripal_feature-relationships.inc";
  24. //require_once "includes/tripal_feature-db_references.inc";
  25. /**
  26. *
  27. * @ingroup tripal_feature
  28. */
  29. function tripal_feature_init() {
  30. drupal_add_js(drupal_get_path('theme', 'tripal') . '/js/tripal_feature.js');
  31. drupal_add_css(drupal_get_path('theme', 'tripal') . '/css/tripal_feature.css');
  32. }
  33. /**
  34. * Implements hook_views_api()
  35. *
  36. * Purpose: Essentially this hook tells drupal that there is views support for
  37. * for this module which then includes tripal_db.views.inc where all the
  38. * views integration code is
  39. *
  40. * @ingroup tripal_feature
  41. */
  42. function tripal_feature_views_api() {
  43. return array(
  44. 'api' => 2.0,
  45. );
  46. }
  47. /**
  48. * Display help and module information
  49. *
  50. * @param
  51. * path which path of the site we're displaying help
  52. * @param
  53. * arg array that holds the current path as would be returned from arg() function
  54. *
  55. * @return
  56. * help text for the path
  57. *
  58. * @ingroup tripal_feature
  59. */
  60. function tripal_feature_help($path, $arg) {
  61. $output = '';
  62. switch ($path) {
  63. case "admin/help#tripal_feature":
  64. $output='<p>' . t("Displays links to nodes created on this date") . '</p>';
  65. break;
  66. }
  67. return $output;
  68. }
  69. /**
  70. * Provide information to drupal about the node types that we're creating
  71. * in this module
  72. *
  73. * @ingroup tripal_feature
  74. */
  75. function tripal_feature_node_info() {
  76. $nodes = array();
  77. $nodes['chado_feature'] = array(
  78. 'name' => t('Feature'),
  79. 'module' => 'chado_feature',
  80. 'description' => t('A feature from the chado database'),
  81. 'has_title' => FALSE,
  82. 'title_label' => t('Feature'),
  83. 'has_body' => FALSE,
  84. 'body_label' => t('Feature Description'),
  85. 'locked' => TRUE
  86. );
  87. return $nodes;
  88. }
  89. /**
  90. * Set the permission types that the chado module uses. Essentially we
  91. * want permissionis that protect creation, editing and deleting of chado
  92. * data objects
  93. *
  94. * @ingroup tripal_feature
  95. */
  96. function tripal_feature_perm() {
  97. return array(
  98. 'access chado_feature content',
  99. 'create chado_feature content',
  100. 'delete chado_feature content',
  101. 'edit chado_feature content',
  102. 'administer tripal features',
  103. );
  104. }
  105. /**
  106. * Implement hook_access().
  107. *
  108. * This hook allows node modules to limit access to the node types they define.
  109. *
  110. * @param $op
  111. * The operation to be performed
  112. *
  113. * @param $node
  114. * The node on which the operation is to be performed, or, if it does not yet exist, the
  115. * type of node to be created
  116. *
  117. * @param $account
  118. * A user object representing the user for whom the operation is to be performed
  119. *
  120. * @return
  121. * If the permission for the specified operation is not set then return FALSE. If the
  122. * permission is set then return NULL as this allows other modules to disable
  123. * access. The only exception is when the $op == 'create'. We will always
  124. * return TRUE if the permission is set.
  125. *
  126. * @ingroup tripal_feature
  127. */
  128. function chado_feature_access($op, $node, $account) {
  129. if ($op == 'create') {
  130. if (!user_access('create chado_feature content', $account)) {
  131. return FALSE;
  132. }
  133. return TRUE;
  134. }
  135. if ($op == 'update') {
  136. if (!user_access('edit chado_feature content', $account)) {
  137. return FALSE;
  138. }
  139. }
  140. if ($op == 'delete') {
  141. if (!user_access('delete chado_feature content', $account)) {
  142. return FALSE;
  143. }
  144. }
  145. if ($op == 'view') {
  146. if (!user_access('access chado_feature content', $account)) {
  147. return FALSE;
  148. }
  149. }
  150. return NULL;
  151. }
  152. /**
  153. * Menu items are automatically added for the new node types created
  154. * by this module to the 'Create Content' Navigation menu item. This function
  155. * adds more menu items needed for this module.
  156. *
  157. * @ingroup tripal_feature
  158. */
  159. function tripal_feature_menu() {
  160. $items = array();
  161. // the administative settings menu
  162. $items['find/sequences'] = array(
  163. 'title' => 'Sequence Retrieval',
  164. 'description' => 'Download a file of sequences',
  165. 'page callback' => 'tripal_feature_seq_extract_page',
  166. 'access arguments' => array('access chado_feature content'),
  167. 'type' => MENU_CALLBACK,
  168. );
  169. $items['find/sequences/ajax'] = array(
  170. 'title' => 'Sequence Retrieval',
  171. 'page callback' => 'tripal_feature_seq_extract_form_ahah_update',
  172. 'access arguments' => array('access chado_feature content'),
  173. 'type' => MENU_CALLBACK,
  174. );
  175. // the administative settings menu
  176. $items['admin/tripal/tripal_feature'] = array(
  177. 'title' => 'Features',
  178. 'description' => 'Basic Description of Tripal Organism Module Functionality',
  179. 'page callback' => 'theme',
  180. 'page arguments' => array('tripal_feature_admin'),
  181. 'access arguments' => array('administer tripal features'),
  182. 'type' => MENU_NORMAL_ITEM,
  183. );
  184. $items['admin/tripal/tripal_feature/configuration'] = array(
  185. 'title' => 'Configuration',
  186. 'description' => 'Configure the Tripal Feature module.',
  187. 'page callback' => 'drupal_get_form',
  188. 'page arguments' => array('tripal_feature_admin'),
  189. 'access arguments' => array('administer tripal features'),
  190. 'type' => MENU_NORMAL_ITEM,
  191. );
  192. $items['admin/tripal/tripal_feature/fasta_loader'] = array(
  193. 'title' => 'Import a multi-FASTA file',
  194. 'description' => 'Load sequences from a multi-FASTA file into Chado',
  195. 'page callback' => 'drupal_get_form',
  196. 'page arguments' => array('tripal_feature_fasta_load_form'),
  197. 'access arguments' => array('administer tripal features'),
  198. 'type' => MENU_NORMAL_ITEM,
  199. );
  200. $items['admin/tripal/tripal_feature/gff3_load'] = array(
  201. 'title' => 'Import a GFF3 file',
  202. 'description' => 'Import a GFF3 file into Chado',
  203. 'page callback' => 'drupal_get_form',
  204. 'page arguments' => array('tripal_feature_gff3_load_form'),
  205. 'access arguments' => array('administer tripal features'),
  206. 'type' => MENU_NORMAL_ITEM,
  207. );
  208. $items['admin/tripal/tripal_feature/delete'] = array(
  209. 'title' => ' Delete Features',
  210. 'description' => 'Delete multiple features from Chado',
  211. 'page callback' => 'drupal_get_form',
  212. 'page arguments' => array('tripal_feature_delete_form'),
  213. 'access arguments' => array('administer tripal features'),
  214. 'type' => MENU_NORMAL_ITEM,
  215. );
  216. $items['admin/tripal/tripal_feature/sync'] = array(
  217. 'title' => ' Sync Features',
  218. 'description' => 'Sync features from Chado with Drupal',
  219. 'page callback' => 'drupal_get_form',
  220. 'page arguments' => array('tripal_feature_sync_form'),
  221. 'access arguments' => array('administer tripal features'),
  222. 'type' => MENU_NORMAL_ITEM,
  223. );
  224. // the menu link for addressing any feature (by name, uniquename, synonym)
  225. $items['feature/%'] = array(
  226. 'title' => 'Matched Features',
  227. 'description' => 'Shows all features that match the provided ID. If multiple features match even by name, uniquename or synonym then a page is presented to allow the user to select which one they intended.',
  228. 'page callback' => 'tripal_feature_match_features_page',
  229. 'page arguments' => array(1),
  230. 'access arguments' => array('access chado_feature content'),
  231. 'type' => MENU_NORMAL_ITEM,
  232. );
  233. return $items;
  234. }
  235. /**
  236. * We need to let drupal know about our theme functions and their arguments.
  237. * We create theme functions to allow users of the module to customize the
  238. * look and feel of the output generated in this module
  239. *
  240. * @ingroup tripal_feature
  241. */
  242. function tripal_feature_theme() {
  243. return array(
  244. 'tripal_feature_search_index' => array(
  245. 'arguments' => array('node'),
  246. ),
  247. 'tripal_feature_search_results' => array(
  248. 'arguments' => array('node'),
  249. ),
  250. 'tripal_organism_feature_browser' => array(
  251. 'arguments' => array('node' => NULL),
  252. 'template' => 'tripal_organism_feature_browser',
  253. ),
  254. 'tripal_organism_feature_counts' => array(
  255. 'arguments' => array('node' => NULL),
  256. 'template' => 'tripal_organism_feature_counts',
  257. ),
  258. 'tripal_feature_base' => array(
  259. 'arguments' => array('node' => NULL),
  260. 'template' => 'tripal_feature_base',
  261. ),
  262. 'tripal_feature_sequence' => array(
  263. 'arguments' => array('node' => NULL),
  264. 'template' => 'tripal_feature_sequence',
  265. ),
  266. 'tripal_feature_synonyms' => array(
  267. 'arguments' => array('node' => NULL),
  268. 'template' => 'tripal_feature_synonyms',
  269. ),
  270. 'tripal_feature_phenotypes' => array(
  271. 'arguments' => array('node' => NULL),
  272. 'template' => 'tripal_feature_phenotypes',
  273. ),
  274. 'tripal_feature_featurepos' => array(
  275. 'arguments' => array('node' => NULL),
  276. 'template' => 'tripal_feature_featurepos',
  277. ),
  278. 'tripal_feature_featureloc_sequences' => array(
  279. 'arguments' => array('node' => NULL),
  280. 'template' => 'tripal_feature_featureloc_sequences',
  281. ),
  282. 'tripal_feature_references' => array(
  283. 'arguments' => array('node' => NULL),
  284. 'template' => 'tripal_feature_references',
  285. ),
  286. 'tripal_feature_properties' => array(
  287. 'arguments' => array('node' => NULL),
  288. 'template' => 'tripal_feature_properties',
  289. ),
  290. 'tripal_feature_terms' => array(
  291. 'arguments' => array('node' => NULL),
  292. 'template' => 'tripal_feature_terms',
  293. ),
  294. 'tripal_feature_alignments' => array(
  295. 'arguments' => array('node' => NULL),
  296. 'template' => 'tripal_feature_alignments',
  297. ),
  298. 'tripal_feature_relationships' => array(
  299. 'arguments' => array('node' => NULL),
  300. 'template' => 'tripal_feature_relationships',
  301. ),
  302. 'tripal_feature_edit_ALL_properties_form' => array(
  303. 'arguments' => array('form' => NULL),
  304. 'function' => 'theme_tripal_feature_edit_ALL_properties_form',
  305. ),
  306. 'tripal_feature_admin' => array(
  307. 'template' => 'tripal_feature_admin',
  308. 'arguments' => array(NULL),
  309. 'path' => drupal_get_path('module', 'tripal_feature') . '/theme'
  310. ),
  311. // themed forms
  312. 'tripal_feature_seq_extract_form' => array(
  313. 'arguments' => array('form'),
  314. )
  315. );
  316. }
  317. /**
  318. *
  319. *
  320. * @ingroup tripal_feature
  321. */
  322. function tripal_feature_block($op = 'list', $delta = 0, $edit=array()) {
  323. switch ($op) {
  324. case 'list':
  325. $blocks['references']['info'] = t('Tripal Feature References');
  326. $blocks['references']['cache'] = BLOCK_NO_CACHE;
  327. $blocks['base']['info'] = t('Tripal Feature Details');
  328. $blocks['base']['cache'] = BLOCK_NO_CACHE;
  329. $blocks['sequence']['info'] = t('Tripal Feature Sequence');
  330. $blocks['sequence']['cache'] = BLOCK_NO_CACHE;
  331. $blocks['featureloc_sequences']['info'] = t('Tripal Feature Annotated Sequence');
  332. $blocks['featureloc_sequences']['cache'] = BLOCK_NO_CACHE;
  333. $blocks['synonyms']['info'] = t('Tripal Feature Synonyms');
  334. $blocks['synonyms']['cache'] = BLOCK_NO_CACHE;
  335. $blocks['properties']['info'] = t('Tripal Feature Properties');
  336. $blocks['properties']['cache'] = BLOCK_NO_CACHE;;
  337. $blocks['terms']['info'] = t('Tripal Annotated Terms');
  338. $blocks['terms']['cache'] = BLOCK_NO_CACHE;;
  339. $blocks['alignments']['info'] = t('Tripal Feature Alignments');
  340. $blocks['alignments']['cache'] = BLOCK_NO_CACHE;
  341. $blocks['relationships']['info'] = t('Tripal Feature Relationships');
  342. $blocks['relationships']['cache'] = BLOCK_NO_CACHE;
  343. $blocks['org_feature_counts']['info'] = t('Tripal Organism Feature Counts');
  344. $blocks['org_feature_counts']['cache'] = BLOCK_NO_CACHE;
  345. $blocks['org_feature_browser']['info'] = t('Tripal Organism Feature Browser');
  346. $blocks['org_feature_browser']['cache'] = BLOCK_NO_CACHE;
  347. return $blocks;
  348. case 'view':
  349. if (user_access('access chado_feature content') and arg(0) == 'node' and is_numeric(arg(1))) {
  350. $nid = arg(1);
  351. $node = node_load($nid);
  352. $block = array();
  353. switch ($delta) {
  354. case 'references':
  355. $block['subject'] = t('References');
  356. $block['content'] = theme('tripal_feature_references', $node);
  357. break;
  358. case 'base':
  359. $block['subject'] = t('Feature Details');
  360. $block['content'] = theme('tripal_feature_base', $node);
  361. break;
  362. case 'synonyms':
  363. $block['subject'] = t('Synonyms');
  364. $block['content'] = theme('tripal_feature_synonyms', $node);
  365. break;
  366. case 'properties':
  367. $block['subject'] = t('Properties');
  368. $block['content'] = theme('tripal_feature_properties', $node);
  369. break;
  370. case 'terms':
  371. $block['subject'] = t('Annotated Terms');
  372. $block['content'] = theme('tripal_feature_terms', $node);
  373. break;
  374. case 'sequence':
  375. $block['subject'] = t('Sequence');
  376. $block['content'] = theme('tripal_feature_sequence', $node);
  377. break;
  378. case 'featureloc_sequences':
  379. $block['subject'] = t('Formatted Sequences');
  380. $block['content'] = theme('tripal_feature_featureloc_sequences', $node);
  381. break;
  382. case 'alignments':
  383. $block['subject'] = t('Alignments');
  384. $block['content'] = theme('tripal_feature_alignments', $node);
  385. break;
  386. case 'relationships':
  387. $block['subject'] = t('Relationships');
  388. $block['content'] = theme('tripal_feature_relationships', $node);
  389. break;
  390. case 'org_feature_counts':
  391. $block['subject'] = t('Feature Type Summary');
  392. $block['content'] = theme('tripal_organism_feature_counts', $node);
  393. break;
  394. case 'org_feature_browser':
  395. $block['subject'] = t('Feature Browser');
  396. $block['content'] = theme('tripal_organism_feature_browser', $node);
  397. break;
  398. case 'library_feature_browser':
  399. $block['subject'] = t('Library Feature Browser');
  400. $block['content'] = theme('tripal_library_feature_browser', $node);
  401. break;
  402. case 'analysis_feature_browser':
  403. $block['subject'] = t('Analysis Feature Browser');
  404. $block['content'] = theme('tripal_analysis_feature_browser', $node);
  405. break;
  406. default :
  407. }
  408. return $block;
  409. }
  410. }
  411. }
  412. /**
  413. * When a new chado_feature node is created we also need to add information
  414. * to our chado_feature table. This function is called on insert of a new node
  415. * of type 'chado_feature' and inserts the necessary information.
  416. *
  417. * @ingroup tripal_feature
  418. */
  419. function chado_feature_insert($node) {
  420. // remove spaces, newlines from residues
  421. $residues = preg_replace("/[\n\r\s]/", "", $node->residues);
  422. $obsolete = 'FALSE';
  423. if ($node->is_obsolete) {
  424. $obsolete = 'TRUE';
  425. }
  426. // check to see if we are inserting a duplicate record.
  427. $values = array(
  428. 'cv_id' => array(
  429. 'name' => 'sequence'
  430. ),
  431. 'name' => $node->feature_type
  432. );
  433. $type = tripal_core_chado_select('cvterm', array('cvterm_id'), $values);
  434. $values = array(
  435. 'organism_id' => $node->organism_id,
  436. 'name' => $node->fname,
  437. 'uniquename' => $node->uniquename,
  438. 'residues' => $residues,
  439. 'seqlen' => drupal_strlen($residues),
  440. 'is_obsolete' => $obsolete,
  441. 'type_id' => $type[0]->cvterm_id,
  442. 'md5checksum' => md5($residues)
  443. );
  444. $options = array('is_duplicate' => TRUE, 'has_record' => TRUE);
  445. $exists = tripal_core_chado_select('feature', array('*'), $values, $options);
  446. // if the record is not a duplicate then add it
  447. if (!$exists) {
  448. $istatus = tripal_core_chado_insert('feature', $values);
  449. if (!$istatus) {
  450. drupal_set_message(t('Unable to add feature.'), 'warning');
  451. watchdog('tripal_feature', 'Insert feature: Unable to create feature where values: %values',
  452. array('%values' => print_r($values, TRUE)), WATCHDOG_WARNING);
  453. }
  454. }
  455. // now get the newly added record
  456. $values = array(
  457. 'organism_id' => $node->organism_id,
  458. 'uniquename' => $node->uniquename,
  459. 'type_id' => $type[0]->cvterm_id,
  460. );
  461. $feature = tripal_core_chado_select('feature', array('feature_id'), $values);
  462. // add the genbank accession and synonyms
  463. chado_feature_add_synonyms($node->synonyms, $feature[0]->feature_id);
  464. // make sure the entry for this feature doesn't already exist in the chado_feature table
  465. // if it doesn't exist then we want to add it.
  466. $node_check_sql = "SELECT * FROM {chado_feature} " .
  467. "WHERE feature_id = '%s'";
  468. $node_check = db_fetch_object(db_query($node_check_sql, $feature[0]->feature_id));
  469. if (!$node_check) {
  470. // next add the item to the drupal table
  471. $sql = "INSERT INTO {chado_feature} (nid, vid, feature_id, sync_date) ".
  472. "VALUES (%d, %d, %d, " . time() . ")";
  473. db_query($sql, $node->nid, $node->vid, $feature[0]->feature_id);
  474. }
  475. }
  476. /**
  477. *
  478. *
  479. * @ingroup tripal_feature
  480. */
  481. function chado_feature_update($node) {
  482. if ($node->revision) {
  483. // there is no way to handle revisions in Chado but leave
  484. // this here just to make not we've addressed it.
  485. }
  486. $residues = preg_replace("/[\n\r\s]/", "", $node->residues);
  487. $obsolete = 'FALSE';
  488. if ($node->is_obsolete) {
  489. $obsolete = 'TRUE';
  490. }
  491. // get the feature type id
  492. $values = array(
  493. 'cv_id' => array(
  494. 'name' => 'sequence'
  495. ),
  496. 'name' => $node->feature_type
  497. );
  498. $type = tripal_core_chado_select('cvterm', array('cvterm_id'), $values);
  499. $feature_id = chado_get_id_for_node('feature', $node->nid) ;
  500. if (sizeof($type) > 0) {
  501. $match = array(
  502. 'feature_id' => $feature_id,
  503. );
  504. $values = array(
  505. 'organism_id' => $node->organism_id,
  506. 'name' => $node->fname,
  507. 'uniquename' => $node->uniquename,
  508. 'residues' => $residues,
  509. 'seqlen' => drupal_strlen($residues),
  510. 'is_obsolete' => $obsolete,
  511. 'type_id' => $type[0]->cvterm_id,
  512. 'md5checksum' => md5($residues)
  513. );
  514. $options = array('return_record' => TRUE);
  515. $status = tripal_core_chado_update('feature', $match, $values, $options);
  516. // add the genbank synonyms
  517. chado_feature_add_synonyms($node->synonyms, $feature_id);
  518. }
  519. else {
  520. drupal_set_message(t('Unable to update feature.'), 'warning');
  521. watchdog('tripal_feature',
  522. 'Update feature: Unable to update feature where values: %values',
  523. array('%values' => print_r($values, TRUE)),
  524. WATCHDOG_WARNING
  525. );
  526. }
  527. }
  528. /**
  529. *
  530. *
  531. * @ingroup tripal_feature
  532. */
  533. function chado_feature_delete($node) {
  534. $feature_id = chado_get_id_for_node('feature', $node->nid);
  535. // if we don't have a library id for this node then this isn't a node of
  536. // type chado_library or the entry in the chado_library table was lost.
  537. if (!$feature_id) {
  538. return;
  539. }
  540. // remove the drupal content
  541. $sql_del = "DELETE FROM {chado_feature} ".
  542. "WHERE nid = %d ".
  543. "AND vid = %d";
  544. db_query($sql_del, $node->nid, $node->vid);
  545. $sql_del = "DELETE FROM {node} ".
  546. "WHERE nid = %d ".
  547. "AND vid = %d";
  548. db_query($sql_del, $node->nid, $node->vid);
  549. $sql_del = "DELETE FROM {node_revisions} ".
  550. "WHERE nid = %d ".
  551. "AND vid = %d";
  552. db_query($sql_del, $node->nid, $node->vid);
  553. // Remove data from feature tables of chado database. This will
  554. // cause a cascade delete and remove all data in referencing tables
  555. // for this feature
  556. chado_query("DELETE FROM {feature} WHERE feature_id = %d", $feature_id);
  557. drupal_set_message(t("The feature and all associated data were removed from") .
  558. "chado");
  559. }
  560. /**
  561. *
  562. *
  563. * @ingroup tripal_feature
  564. */
  565. function chado_feature_add_synonyms($synonyms, $feature_id) {
  566. // separate synomys by carriage returns
  567. $synonyms = preg_replace("/[\n\r]+/", " ", $synonyms);
  568. // split the synonyms into an array based on a space as the delimieter
  569. $syn_array = array();
  570. $syn_array = explode(" ", $synonyms);
  571. // remove any old synonyms
  572. $feature_syn_dsql = "DELETE FROM {feature_synonym} WHERE feature_id = %d";
  573. if (!chado_query($feature_syn_dsql, $feature_id)) {
  574. $error .= "Could not remove synonyms from feature. ";
  575. }
  576. // return if we don't have any synonmys to add
  577. if (!$synonyms) {
  578. return;
  579. }
  580. // iterate through each synonym and add it to the database
  581. foreach ($syn_array as $syn) {
  582. // skip this item if it's empty
  583. if (!$syn) {
  584. break; }
  585. // check to see if we have this accession number already in the database
  586. // if so then don't add it again. it messes up drupal if the insert fails.
  587. // It is possible for the accession number to be present and not the feature
  588. $synonym_sql = "SELECT synonym_id FROM {synonym} ".
  589. "WHERE name = '%s'";
  590. $synonym = db_fetch_object(chado_query($synonym_sql, $syn));
  591. if (!$synonym) {
  592. $synonym_isql = "INSERT INTO {synonym} (name,synonym_sgml,type_id) ".
  593. "VALUES ('%s','%s', ".
  594. " (SELECT cvterm_id ".
  595. " FROM {CVTerm} CVT ".
  596. " INNER JOIN CV ON CVT.cv_id = CV.cv_id ".
  597. " WHERE CV.name = 'feature_property' and CVT.name = 'synonym'))";
  598. if (!chado_query($synonym_isql, $syn, $syn)) {
  599. $error .= "Could not add synonym. ";
  600. }
  601. // now get the synonym we just added
  602. $synonym_sql = "SELECT synonym_id FROM {synonym} ".
  603. "WHERE name = '%s'";
  604. $synonym = db_fetch_object(chado_query($synonym_sql, $syn));
  605. }
  606. // now add in our new sysnonym
  607. $feature_syn_isql = "INSERT INTO {feature_synonym} (synonym_id,feature_id,pub_id) ".
  608. "VALUES (%d,%d,1)";
  609. if (!chado_query($feature_syn_isql, $synonym->synonym_id, $feature_id)) {
  610. $error .= "Could not add synonyms to feature. ";
  611. }
  612. }
  613. // return to the drupal database
  614. return $error;
  615. }
  616. /**
  617. *
  618. *
  619. * @ingroup tripal_feature
  620. */
  621. function chado_feature_add_gbaccession($accession, $feature_id) {
  622. // use chado database
  623. // remove any old accession from genbank dbEST
  624. $fdbxref_dsql = "DELETE FROM {feature_dbxref} ".
  625. "WHERE feature_id = %d and dbxref_id IN ".
  626. " (SELECT DBX.dbxref_id FROM {dbxref} DBX ".
  627. " INNER JOIN DB ON DB.db_id = DBX.db_id ".
  628. " INNER JOIN feature_dbxref FDBX ON DBX.dbxref_id = FDBX.dbxref_id ".
  629. " WHERE DB.name = 'DB:Genbank' and FDBX.feature_id = %d)";
  630. if (!chado_query($fdbxref_dsql, $feature_id, $feature_id)) {
  631. $error .= "Could not remove accession from feature. ";
  632. }
  633. // if we don't have an accession number to add then just return
  634. if (!$accession) {
  635. return;
  636. }
  637. // get the db_id
  638. $db_sql = "SELECT db_id FROM {DB} ".
  639. "WHERE name = 'DB:Genbank_est'";
  640. $db = db_fetch_object(chado_query($db_sql));
  641. // check to see if we have this accession number already in the database
  642. // if so then don't add it again. it messes up drupal if the insert fails.
  643. // It is possible for the accession number to be present and not the feature
  644. $dbxref_sql = "SELECT dbxref_id FROM {dbxref} ".
  645. "WHERE db_id = %d and accession = '%s'";
  646. $dbxref = db_fetch_object(chado_query($dbxref_sql, $db->db_id, $accession));
  647. if (!$dbxref) {
  648. // add the accession number
  649. $dbxref_isql = "INSERT INTO {dbxref} (db_id,accession) ".
  650. " VALUES (%d, '%s') ";
  651. if (!chado_query($dbxref_isql, $db->db_id, $accession)) {
  652. $error .= 'Could not add accession as a database reference ';
  653. }
  654. // get the dbxref_id for the just added accession number
  655. $dbxref_sql = "SELECT dbxref_id FROM {dbxref} ".
  656. "WHERE db_id = %d and accession = '%s'";
  657. $dbxref = db_fetch_object(chado_query($dbxref_sql, $db->db_id, $accession));
  658. }
  659. // associate the accession number with the feature
  660. $feature_dbxref_isql = "INSERT INTO {feature_dbxref} (feature_id,dbxref_id) ".
  661. " VALUES (%d, %d) ";
  662. if (!chado_query($feature_dbxref_isql, $feature_id, $dbxref->dbxref_id)) {
  663. $error .= 'Could not add feature database reference. ';
  664. }
  665. return $error;
  666. }
  667. /**
  668. *
  669. *
  670. * @ingroup tripal_feature
  671. */
  672. function chado_feature_form($node, $param) {
  673. $type = node_get_types('type', $node);
  674. $form = array();
  675. $feature = $node->feature;
  676. // add the residues to the feature object
  677. $feature = tripal_core_expand_chado_vars($feature, 'field', 'feature.residues');
  678. // if the node has synonyms then use that as the form may be returning
  679. // from an error. Otherwise try to find synonyms from the database
  680. $synonyms = $node->synonyms;
  681. $feature = tripal_core_expand_chado_vars($feature, 'table', 'feature_synonym');
  682. $feature_synonyms = $feature->feature_synonym;
  683. if (!$synonyms) {
  684. if (!is_array($feature_synonyms)) {
  685. $synonyms = $feature_synonyms->synonym_id->name;
  686. }
  687. elseif (is_array($feature_synonyms)) {
  688. foreach ($feature_synonyms as $index => $synonym) {
  689. $synonyms .= $synonym->synonym_id->name . "\n";
  690. }
  691. }
  692. }
  693. $analyses = $node->analyses;
  694. $references = $node->references;
  695. // We need to pass above variables for preview to show
  696. $form['feature'] = array(
  697. '#type' => 'value',
  698. '#value' => $feature
  699. );
  700. // This field is read when previewing a node
  701. $form['synonyms'] = array(
  702. '#type' => 'value',
  703. '#value' => $synonyms
  704. );
  705. // This field is read when previewing a node
  706. $form['analyses'] = array(
  707. '#type' => 'value',
  708. '#value' => $analyses
  709. );
  710. // This field is read when previewing a node
  711. $form['references'] = array(
  712. '#type' => 'value',
  713. '#value' => $references
  714. );
  715. // keep track of the feature id if we have one. If we do have one then
  716. // this would indicate an update as opposed to an insert.
  717. $form['feature_id'] = array(
  718. '#type' => 'value',
  719. '#value' => $feature->feature_id,
  720. );
  721. $form['title']= array(
  722. '#type' => 'textfield',
  723. '#title' => t('Title'),
  724. '#required' => TRUE,
  725. '#default_value' => $node->title,
  726. '#description' => t('The title must be a unique identifier for this feature. It is recommended to use a combination of uniquename, organism and feature type in the title as this is guranteed to be unique.'),
  727. '#maxlength' => 255
  728. );
  729. $form['uniquename']= array(
  730. '#type' => 'textfield',
  731. '#title' => t('Unique Feature Name'),
  732. '#required' => TRUE,
  733. '#default_value' => $feature->uniquename,
  734. '#description' => t('Enter a unique name for this feature. This name must be unique for the organism and feature type.'),
  735. '#maxlength' => 255
  736. );
  737. $form['fname']= array(
  738. '#type' => 'textfield',
  739. '#title' => t('Feature Name'),
  740. '#required' => TRUE,
  741. '#default_value' => $feature->name,
  742. '#description' => t('Enter the name used by humans to refer to this feature.'),
  743. '#maxlength' => 255
  744. );
  745. // get the sequence ontology CV ID
  746. $values = array('name' => 'sequence');
  747. $cv = tripal_core_chado_select('cv', array('cv_id'), $values);
  748. $cv_id = $cv[0]->cv_id;
  749. $form['feature_type'] = array(
  750. '#title' => t('Feature Type'),
  751. '#type' => 'textfield',
  752. '#description' => t("Choose the feature type."),
  753. '#required' => TRUE,
  754. '#default_value' => $feature->type_id->name,
  755. '#autocomplete_path' => "admin/tripal/tripal_cv/cvterm/auto_name/$cv_id",
  756. );
  757. // get the list of organisms
  758. $sql = "SELECT * FROM {Organism} ORDER BY genus, species";
  759. $org_rset = chado_query($sql);
  760. $organisms = array();
  761. $organisms[''] = '';
  762. while ($organism = db_fetch_object($org_rset)) {
  763. $organisms[$organism->organism_id] = "$organism->genus $organism->species ($organism->common_name)";
  764. }
  765. $form['organism_id'] = array(
  766. '#title' => t('Organism'),
  767. '#type' => t('select'),
  768. '#description' => t("Choose the organism with which this feature is associated"),
  769. '#required' => TRUE,
  770. '#default_value' => $feature->organism_id->organism_id,
  771. '#options' => $organisms,
  772. );
  773. // Get synonyms
  774. if ($synonyms) {
  775. if (is_array($synonyms)) {
  776. foreach ($synonyms as $synonym) {
  777. $syn_text .= "$synonym->name\n";
  778. }
  779. }
  780. else {
  781. $syn_text = $synonyms;
  782. }
  783. }
  784. $form['synonyms']= array(
  785. '#type' => 'textarea',
  786. '#title' => t('Synonyms'),
  787. '#required' => FALSE,
  788. '#default_value' => $syn_text,
  789. '#description' => t('Enter alternate names (synonmys) for this feature to help in searching and identification. You may enter as many alternate names as needed each on different lines.'),
  790. );
  791. $form['residues']= array(
  792. '#type' => 'textarea',
  793. '#title' => t('Residues'),
  794. '#required' => FALSE,
  795. '#default_value' => $feature->residues,
  796. '#description' => t('Enter the nucelotide sequences for this feature'),
  797. );
  798. $checked = '';
  799. if ($feature->is_obsolete == 't') {
  800. $checked = '1';
  801. }
  802. $form['is_obsolete']= array(
  803. '#type' => 'checkbox',
  804. '#title' => t('Is Obsolete'),
  805. '#required' => FALSE,
  806. '#default_value' => $checked,
  807. '#description' => t('Check this box if this sequence should be retired and no longer included in further analysis.'),
  808. );
  809. return $form;
  810. }
  811. /**
  812. *
  813. *
  814. * @ingroup tripal_feature
  815. */
  816. function chado_feature_validate($node) {
  817. $result = 0;
  818. // make sure the feature type is a real sequence ontology term
  819. $type = tripal_cv_get_cvterm_by_name($node->feature_type, NULL, 'sequence');
  820. if (!$type) {
  821. form_set_error('feature_type', t("The feature type is not a valid name from the Sequence Ontology."));
  822. }
  823. // if this is an update, we want to make sure that a different feature for
  824. // the organism doesn't already have this uniquename. We don't want to give
  825. // two sequences the same uniquename
  826. if ($node->feature_id) {
  827. $sql = "SELECT *
  828. FROM {Feature} F
  829. INNER JOIN {cvterm} CVT ON F.type_id = CVT.cvterm_id
  830. WHERE uniquename = '%s'
  831. AND organism_id = %d AND CVT.name = '%s' AND NOT feature_id = %d";
  832. $result = db_fetch_object(chado_query($sql, $node->uniquename, $node->organism_id, $node->feature_type, $node->feature_id));
  833. if ($result) {
  834. form_set_error('uniquename', t("Feature update cannot proceed. The feature name '$node->uniquename' is not unique for this organism. Please provide a unique name for this feature."));
  835. }
  836. }
  837. // if this is an insert then we just need to make sure this name doesn't
  838. // already exist for this organism if it does then we need to throw an error
  839. else {
  840. $sql = "SELECT *
  841. FROM {Feature} F
  842. INNER JOIN {cvterm} CVT ON F.type_id = CVT.cvterm_id
  843. WHERE uniquename = '%s'
  844. AND organism_id = %d AND CVT.name = '%s'";
  845. $result = db_fetch_object(chado_query($sql, $node->uniquename, $node->organism_id, $node->feature_type));
  846. if ($result) {
  847. form_set_error('uniquename', t("Feature insert cannot proceed. The feature name '$node->uniquename' already exists for this organism. Please provide a unique name for this feature."));
  848. }
  849. }
  850. // we don't allow a genbank accession number for a contig
  851. if ($node->feature_type == 'contig' and $node->gbaccession) {
  852. form_set_error('gbaccession', t("Contigs cannot have a genbank accession number. Please change the feature type or remove the accession number"));
  853. }
  854. }
  855. /**
  856. * When a node is requested by the user this function is called to allow us
  857. * to add auxiliary data to the node object.
  858. *
  859. * @ingroup tripal_feature
  860. */
  861. function chado_feature_load($node) {
  862. // get the feature details from chado
  863. $feature_id = chado_get_id_for_node('feature', $node->nid);
  864. $values = array('feature_id' => $feature_id);
  865. $feature = tripal_core_generate_chado_var('feature', $values);
  866. if (strcmp($feature->name, $feature->uniquename)==0) {
  867. $node->title = $feature->name . " (" . $feature->type_id->name . ") " . $feature->organism_id->genus . " " . $feature->organism_id->species ;
  868. }
  869. $additions = new stdClass();
  870. $additions->feature = $feature;
  871. return $additions;
  872. }
  873. /**
  874. *
  875. *
  876. * @ingroup tripal_feature
  877. */
  878. function tripal_feature_load_organism($organism_id) {
  879. // add organism details
  880. $sql = "SELECT * FROM {organism} WHERE organism_id = %d";
  881. $organism = db_fetch_object(chado_query($sql, $organism_id));
  882. return $organism;
  883. }
  884. /**
  885. *
  886. *
  887. * @ingroup tripal_feature
  888. */
  889. function tripal_feature_load_synonyms($feature_id) {
  890. $sql = "SELECT S.name ".
  891. "FROM {Feature_Synonym} FS ".
  892. " INNER JOIN {Synonym} S ".
  893. " ON FS.synonym_id = S.Synonym_id ".
  894. "WHERE FS.feature_id = %d ".
  895. "ORDER BY S.name ";
  896. $results = chado_query($sql, $feature_id);
  897. $synonyms = array();
  898. $i=0;
  899. while ($synonym = db_fetch_object($results)) {
  900. $synonyms[$i++] = $synonym;
  901. }
  902. return $synonyms;
  903. }
  904. /**
  905. *
  906. *
  907. * @ingroup tripal_feature
  908. */
  909. function tripal_feature_load_properties($feature_id) {
  910. $sql = "SELECT CVT.name as cvname, FS.type_id, FS.value, FS.rank,
  911. CVT.definition, CVT.is_obsolete,
  912. DBX.dbxref_id,DBX.accession,DB.name as dbname,
  913. DB.urlprefix, DB.description as db_description, DB.url
  914. FROM {featureprop} FS
  915. INNER JOIN {cvterm} CVT ON FS.type_id = CVT.cvterm_id
  916. INNER JOIN {dbxref} DBX ON CVT.dbxref_id = DBX.dbxref_id
  917. INNER JOIN {db} DB ON DB.db_id = DBX.db_id
  918. WHERE FS.feature_id = %d
  919. ORDER BY FS.rank ASC";
  920. $results = chado_query($sql, $feature_id);
  921. $i=0;
  922. $properties = array();
  923. while ($property = db_fetch_object($results)) {
  924. $properties[$i++] = $property;
  925. }
  926. return $properties;
  927. }
  928. /**
  929. *
  930. *
  931. * @ingroup tripal_feature
  932. */
  933. function tripal_feature_load_references($feature_id) {
  934. $sql = "SELECT F.uniquename,F.Feature_id,DBX.accession,DB.description as dbdesc, ".
  935. " DB.db_id, DB.name as db_name, DB.urlprefix,DBX.dbxref_id ".
  936. "FROM {feature} F ".
  937. " INNER JOIN {feature_dbxref} FDBX on F.feature_id = FDBX.feature_id ".
  938. " INNER JOIN {dbxref} DBX on DBX.dbxref_id = FDBX.dbxref_id ".
  939. " INNER JOIN {db} on DB.db_id = DBX.db_id ".
  940. "WHERE F.feature_id = %d ".
  941. "ORDER BY DB.name ";
  942. $results = chado_query($sql, $feature_id);
  943. $references = array();
  944. $i=0;
  945. while ($accession = db_fetch_object($results)) {
  946. $references[$i++] = $accession;
  947. }
  948. return $references;
  949. }
  950. /**
  951. *
  952. *
  953. * @ingroup tripal_feature
  954. */
  955. function tripal_feature_load_featurelocs($feature_id, $side = 'as_parent', $aggregate = 1) {
  956. $sql = "SELECT
  957. F.name, F.feature_id, F.uniquename,
  958. FS.name as src_name,
  959. FS.feature_id as src_feature_id,
  960. FS.uniquename as src_uniquename,
  961. CVT.name as cvname, CVT.cvterm_id,
  962. CVTS.name as src_cvname, CVTS.cvterm_id as src_cvterm_id,
  963. FL.fmin, FL.fmax, FL.is_fmin_partial, FL.is_fmax_partial,FL.strand,
  964. FL.phase
  965. FROM {featureloc} FL
  966. INNER JOIN {feature} F on FL.feature_id = F.feature_id
  967. INNER JOIN {feature} FS on FS.feature_id = FL.srcfeature_id
  968. INNER JOIN {cvterm} CVT on F.type_id = CVT.cvterm_id
  969. INNER JOIN {cvterm} CVTS on FS.type_id = CVTS.cvterm_id
  970. ";
  971. if (strcmp($side, 'as_parent')==0) {
  972. $sql .= "WHERE FL.srcfeature_id = %d ";
  973. }
  974. if (strcmp($side, 'as_child')==0) {
  975. $sql .= "WHERE FL.feature_id = %d ";
  976. }
  977. $flresults = chado_query($sql, $feature_id);
  978. // copy the results into an array
  979. $i=0;
  980. $featurelocs = array();
  981. while ($loc = db_fetch_object($flresults)) {
  982. // if a drupal node exists for this feature then add the nid to the
  983. // results object
  984. $sql = 'SELECT nid FROM {chado_feature} WHERE feature_id = %d';
  985. $ffeature = db_fetch_object(db_query($sql, $loc->feature_id));
  986. $sfeature = db_fetch_object(db_query($sql, $loc->src_feature_id));
  987. $loc->fnid = $ffeature->nid;
  988. $loc->snid = $sfeature->nid;
  989. // add the result to the array
  990. $featurelocs[$i++] = $loc;
  991. }
  992. // Add the relationship feature locs if aggregate is turned on
  993. if ($aggregate and strcmp($side, 'as_parent')==0) {
  994. // get the relationships for this feature without substituting any children
  995. // for the parent. We want all relationships
  996. $relationships = tripal_feature_get_aggregate_relationships($feature_id, 0);
  997. foreach ($relationships as $rindex => $rel) {
  998. // get the featurelocs for each of the relationship features
  999. $rel_featurelocs = tripal_feature_load_featurelocs($rel->subject_id, 'as_child', 0);
  1000. foreach ($rel_featurelocs as $findex => $rfloc) {
  1001. $featurelocs[$i++] = $rfloc;
  1002. }
  1003. }
  1004. }
  1005. usort($featurelocs, 'tripal_feature_sort_locations');
  1006. return $featurelocs;
  1007. }
  1008. /**
  1009. * used to sort the feature locs by start position
  1010. *
  1011. * @ingroup tripal_feature
  1012. */
  1013. function tripal_feature_sort_locations($a, $b) {
  1014. return strnatcmp($a->fmin, $b->fmin);
  1015. }
  1016. /**
  1017. *
  1018. *
  1019. * @ingroup tripal_feature
  1020. */
  1021. function tripal_feature_load_relationships($feature_id, $side = 'as_subject') {
  1022. // get the relationships for this feature. The query below is used for both
  1023. // querying the object and subject relationships
  1024. $sql = "SELECT
  1025. FS.name as subject_name,
  1026. FS.uniquename as subject_uniquename,
  1027. CVTS.name as subject_type,
  1028. CVTS.cvterm_id as subject_type_id,
  1029. FR.subject_id,
  1030. FR.type_id as relationship_type_id,
  1031. CVT.name as rel_type,
  1032. FO.name as object_name,
  1033. FO.uniquename as object_uniquename,
  1034. CVTO.name as object_type,
  1035. CVTO.cvterm_id as object_type_id,
  1036. FR.object_id,
  1037. FR.rank
  1038. FROM {feature_relationship} FR
  1039. INNER JOIN {cvterm} CVT ON FR.type_id = CVT.cvterm_id
  1040. INNER JOIN {feature} FS ON FS.feature_id = FR.subject_id
  1041. INNER JOIN {feature} FO ON FO.feature_id = FR.object_id
  1042. INNER JOIN {cvterm} CVTO ON FO.type_id = CVTO.cvterm_id
  1043. INNER JOIN {cvterm} CVTS ON FS.type_id = CVTS.cvterm_id
  1044. ";
  1045. if (strcmp($side, 'as_object')==0) {
  1046. $sql .= " WHERE FR.object_id = %d";
  1047. }
  1048. if (strcmp($side, 'as_subject')==0) {
  1049. $sql .= " WHERE FR.subject_id = %d";
  1050. }
  1051. $sql .= " ORDER BY FR.rank";
  1052. // get the relationships
  1053. $results = chado_query($sql, $feature_id);
  1054. // iterate through the relationships, put these in an array and add
  1055. // in the Drupal node id if one exists
  1056. $i=0;
  1057. $nodesql = "SELECT nid FROM {chado_feature} WHERE feature_id = %d";
  1058. $relationships = array();
  1059. while ($rel = db_fetch_object($results)) {
  1060. $node = db_fetch_object(db_query($nodesql, $rel->subject_id));
  1061. if ($node) {
  1062. $rel->subject_nid = $node->nid;
  1063. }
  1064. $node = db_fetch_object(db_query($nodesql, $rel->object_id));
  1065. if ($node) {
  1066. $rel->object_nid = $node->nid;
  1067. }
  1068. $relationships[$i++] = $rel;
  1069. }
  1070. return $relationships;
  1071. }
  1072. /**
  1073. *
  1074. *
  1075. * @ingroup tripal_feature
  1076. */
  1077. function tripal_feature_get_aggregate_relationships($feature_id, $substitute=1,
  1078. $levels=0, $base_type_id=NULL, $depth=0) {
  1079. // we only want to recurse to as many levels deep as indicated by the
  1080. // $levels variable, but only if this variable is > 0. If 0 then we
  1081. // recurse until we reach the end of the relationships tree.
  1082. if ($levels > 0 and $levels == $depth) {
  1083. return NULL;
  1084. }
  1085. // first get the relationships for this feature
  1086. return tripal_feature_load_relationships($feature_id, 'as_object');
  1087. }
  1088. /**
  1089. *
  1090. *
  1091. * @ingroup tripal_feature
  1092. */
  1093. function tripal_feature_load_featureloc_sequences($feature_id, $featurelocs) {
  1094. // if we don't have any featurelocs then no point in continuing
  1095. if (!$featurelocs) {
  1096. return array();
  1097. }
  1098. // get the list of relationships (including any aggregators) and iterate
  1099. // through each one to find information needed to color-code the reference sequence
  1100. $relationships = tripal_feature_get_aggregate_relationships($feature_id);
  1101. if (!$relationships) {
  1102. return array();
  1103. }
  1104. // iterate through each of the realtionships features and get their
  1105. // locations
  1106. foreach ($relationships as $rindex => $rel) {
  1107. // get the featurelocs for each of the relationship features
  1108. $rel_featurelocs = tripal_feature_load_featurelocs($rel->subject_id, 'as_child', 0);
  1109. foreach ($rel_featurelocs as $rfindex => $rel_featureloc) {
  1110. // keep track of this unique source feature
  1111. $src = $rel_featureloc->src_feature_id ."-". $rel_featureloc->src_cvterm_id;
  1112. // copy over the results to the relationship object. Since there can
  1113. // be more than one feature location for each relationship feature we
  1114. // use the '$src' variable to keep track of these.
  1115. $rel->featurelocs->$src->src_uniquename = $rel_featureloc->src_uniquename;
  1116. $rel->featurelocs->$src->src_cvterm_id = $rel_featureloc->src_cvterm_id;
  1117. $rel->featurelocs->$src->src_cvname = $rel_featureloc->src_cvname;
  1118. $rel->featurelocs->$src->fmin = $rel_featureloc->fmin;
  1119. $rel->featurelocs->$src->fmax = $rel_featureloc->fmax;
  1120. $rel->featurelocs->$src->src_name = $rel_featureloc->src_name;
  1121. // keep track of the individual parts for each relationship
  1122. $start = $rel->featurelocs->$src->fmin;
  1123. $end = $rel->featurelocs->$src->fmax;
  1124. $type = $rel->subject_type;
  1125. $rel_locs[$src]['parts'][$start][$type]['start'] = $start;
  1126. $rel_locs[$src]['parts'][$start][$type]['end'] = $end;
  1127. $rel_locs[$src]['parts'][$start][$type]['type'] = $type;
  1128. }
  1129. }
  1130. // the featurelocs array provided to the function contains the locations
  1131. // where this feature is found. We want to get the sequence for each
  1132. // location and then annotate it with the parts found from the relationships
  1133. // locations determiend above.
  1134. $sql = "SELECT substring(residues from %d for %d) as residues ".
  1135. "FROM {feature} ".
  1136. "WHERE feature_id = %d";
  1137. $floc_sequences = array();
  1138. foreach ($featurelocs as $featureloc) {
  1139. // build the src name so we can keep track of the different parts for each feature
  1140. $src = $featureloc->srcfeature_id->feature_id ."-". $featureloc->srcfeature_id->type_id->cvterm_id;
  1141. // orient the parts to the beginning of the feature sequence
  1142. if (!empty($rel_locs[$src]['parts'])) {
  1143. $parts = $rel_locs[$src]['parts'];
  1144. $rparts = array(); // we will fill this up if we're on the reverse strand
  1145. foreach ($parts as $start => $types) {
  1146. foreach ($types as $type_name => $type) {
  1147. if ($featureloc->strand >= 0) {
  1148. // this is on the forward strand. We need to convert the start on the src feature to the
  1149. // start on this feature's sequence
  1150. $parts[$start][$type_name]['start'] = $parts[$start][$type_name]['start'] - $featureloc->fmin;
  1151. $parts[$start][$type_name]['end'] = $parts[$start][$type_name]['end'] - $featureloc->fmin;
  1152. $parts[$start][$type_name]['type'] = $type_name;
  1153. }
  1154. else {
  1155. // this is on the reverse strand. We need to swap the start and stop and calculate from the
  1156. // begining of the reverse sequence
  1157. $size = ($featureloc->fmax - $featureloc->fmin);
  1158. $start_orig = $parts[$start][$type_name]['start'];
  1159. $end_orig = $parts[$start][$type_name]['end'];
  1160. $new_start = $size - ($end_orig - $featureloc->fmin);
  1161. $new_end = $size - ($start_orig - $featureloc->fmin);
  1162. $rparts[$new_start][$type_name]['start'] = $new_start;
  1163. $rparts[$new_start][$type_name]['end'] = $new_end;
  1164. $rparts[$new_start][$type_name]['type'] = $type_name;
  1165. }
  1166. }
  1167. }
  1168. // now sort the parts
  1169. // if we're on the reverse strand we need to resort
  1170. if ($featureloc->strand >= 0) {
  1171. usort($parts, 'tripal_feature_sort_rel_parts_by_start');
  1172. }
  1173. else {
  1174. usort($rparts, 'tripal_feature_sort_rel_parts_by_start');
  1175. $parts = $rparts;
  1176. }
  1177. $floc_sequences[$src]['src'] = $src;
  1178. $floc_sequences[$src]['type'] = $featureloc->feature_id->type_id->name;
  1179. $sequence = db_fetch_object(chado_query($sql, $featureloc->fmin + 1, ($featureloc->fmax - $featureloc->fmin), $featureloc->srcfeature_id->feature_id));
  1180. $residues = $sequence->residues;
  1181. if ($featureloc->strand < 0) {
  1182. $residues = tripal_feature_reverse_complement($residues);
  1183. }
  1184. $strand = '.';
  1185. if ($featureloc->strand == 1) {
  1186. $strand = '+';
  1187. }
  1188. elseif ($featureloc->strand == -1) {
  1189. $strand = '-';
  1190. }
  1191. $defline = $featureloc->feature_id->name . " " . $featureloc->srcfeature_id->name . ":" . ($featureloc->fmin + 1) . ".." . $featureloc->fmax . " " . $strand;
  1192. $floc_sequences[$src]['formatted_seq'] = tripal_feature_color_sequence($residues, $parts, $defline);
  1193. }
  1194. }
  1195. return $floc_sequences;
  1196. }
  1197. /**
  1198. *
  1199. *
  1200. * @ingroup tripal_feature
  1201. */
  1202. function tripal_feature_get_matched_alignments($feature) {
  1203. // This function is for features that align through an intermediate such
  1204. // as 'EST_match' or 'match'. This occurs in the case where two sequences
  1205. // align but where one does not align perfectly. Some ESTs may be in a contig
  1206. // but not all of the EST. Portions may overhang and not be included in the
  1207. // consensus if quality is bad.
  1208. // For example:
  1209. //
  1210. // Feature 1: Contig --------------------
  1211. // Feature 2: EST_match -------
  1212. // Feature 3: EST ---------
  1213. //
  1214. // The feature provided to the function will always be the feature 1. The
  1215. // featureloc columns prefixed with 'right' (e.g. right_fmin) belong to the
  1216. // alignment of feature 3 with feature 2
  1217. //
  1218. // Features may align to more than one feature and are not matches. We do
  1219. // not want to include these, so we have to filter on the SO terms:
  1220. // match, or %_match
  1221. //
  1222. $sql = "SELECT ".
  1223. " FL1.featureloc_id as left_featureloc_id, ".
  1224. " FL1.srcfeature_id as left_srcfeature_id, ".
  1225. " FL1.feature_id as left_feature_id, ".
  1226. " FL1.fmin as left_fmin, ".
  1227. " FL1.is_fmin_partial as left_is_fmin_partial, ".
  1228. " FL1.fmax as left_fmax, ".
  1229. " FL1.is_fmax_partial as left_is_fmax_partial, ".
  1230. " FL1.strand as left_strand, ".
  1231. " FL1.phase as left_phase, ".
  1232. " FL1.locgroup as left_locgroup, ".
  1233. " FL1.rank as left_rank, ".
  1234. " FL2.featureloc_id as right_featureloc_id, ".
  1235. " FL2.srcfeature_id as right_srcfeature_id, ".
  1236. " FL2.feature_id as right_feature_id, ".
  1237. " FL2.fmin as right_fmin, ".
  1238. " FL2.is_fmin_partial as right_is_fmin_partial, ".
  1239. " FL2.fmax as right_fmax, ".
  1240. " FL2.is_fmax_partial as right_is_fmax_partial, ".
  1241. " FL2.strand as right_strand, ".
  1242. " FL2.phase as right_phase, ".
  1243. " FL2.locgroup as right_locgroup, ".
  1244. " FL2.rank as right_rank ".
  1245. "FROM {feature} F1 ".
  1246. " INNER JOIN {featureloc} FL1 on FL1.srcfeature_id = F1.feature_id ".
  1247. " INNER JOIN {feature} F2 on FL1.feature_id = F2.feature_id ".
  1248. " INNER JOIN {featureloc} FL2 on FL2.feature_id = F2.feature_id ".
  1249. " INNER JOIN {feature} F3 on FL2.srcfeature_id = F3.feature_id ".
  1250. " INNER JOIN {cvterm} CVT2 on F2.type_id = CVT2.cvterm_id ".
  1251. "WHERE F1.feature_id = %d and NOT F3.feature_id = %d ".
  1252. " AND (CVT2.name = 'match' or CVT2.name like '%_match') ".
  1253. "ORDER BY FL1.fmin";
  1254. $results = chado_query($sql, $feature->feature_id, $feature->feature_id);
  1255. // iterate through the results and add them to our featurelocs array
  1256. $featurelocs = array();
  1257. while ($fl = db_fetch_object($results)) {
  1258. $featurelocs[] = $fl ;
  1259. }
  1260. return $featurelocs;
  1261. }
  1262. /**
  1263. *
  1264. *
  1265. * @ingroup tripal_feature
  1266. */
  1267. function tripal_feature_load_organism_feature_counts($organism) {
  1268. // don't show the browser if the settings in the admin page is turned off
  1269. // instead return the array indicating the status of the browser
  1270. $show_counts = variable_get('tripal_feature_summary_setting', 'show_feature_summary');
  1271. if (strcmp($show_counts, 'show_feature_summary')!=0) {
  1272. return array('enabled' => FALSE );
  1273. }
  1274. $args = array();
  1275. $names = array();
  1276. $order = array();
  1277. // build the where clause for the SQL statement if we have a custom term list
  1278. // we'll also keep track of the names the admin provided (if any) and the
  1279. // order that the terms should appear.
  1280. $is_custom = 0;
  1281. $temp = rtrim(variable_get('tripal_feature_summary_report_mapping', ''));
  1282. $where = '';
  1283. if ($temp) {
  1284. $is_custom = 1;
  1285. $temp = explode("\n", $temp);
  1286. foreach ($temp as $key => $value) {
  1287. // separate the key value pairs
  1288. $temp2 = explode("=", $value);
  1289. $feature_type = rtrim($temp2[0]);
  1290. $args[] = $feature_type;
  1291. $order[] = $feature_type;
  1292. // if a new name is provided then use that otherwise just
  1293. // use the feature type
  1294. if (count($temp2) == 2) {
  1295. $names[] = rtrim($temp2[1]);
  1296. }
  1297. else {
  1298. $names[] = $feature_type;
  1299. }
  1300. $where .= "OFC.feature_type = '%s' OR \n";
  1301. }
  1302. if ($where) {
  1303. $where = drupal_substr($where, 0, -5); # remove OR from the end
  1304. $where = "($where) AND";
  1305. }
  1306. }
  1307. // get the feature counts. This is dependent on a materialized view
  1308. // installed with the organism module
  1309. $sql = "
  1310. SELECT OFC.num_features,OFC.feature_type,CVT.definition
  1311. FROM {organism_feature_count} OFC
  1312. INNER JOIN {cvterm} CVT on OFC.cvterm_id = CVT.cvterm_id
  1313. WHERE $where organism_id = %d
  1314. ORDER BY num_features desc
  1315. ";
  1316. $args[] = $organism->organism_id;
  1317. $org_features = chado_query($sql, $args);
  1318. // iterate through the types
  1319. $types = array();
  1320. while ($type = db_fetch_object($org_features)) {
  1321. $types[$type->feature_type] = $type;
  1322. // if we don't have an order this means we didn't go through the loop
  1323. // above to set the names, so do that now
  1324. if (!$is_custom) {
  1325. $names[] = $type->feature_type;
  1326. $order[] = $type->feature_type;
  1327. }
  1328. }
  1329. # now reorder the types
  1330. $ordered_types = array();
  1331. foreach ($order as $type) {
  1332. $ordered_types[] = $types[$type];
  1333. }
  1334. return array( 'types' => $ordered_types, 'names' => $names, 'enabled' => TRUE );
  1335. }
  1336. /**
  1337. *
  1338. *
  1339. * @ingroup tripal_feature
  1340. */
  1341. function tripal_feature_load_organism_feature_browser($organism) {
  1342. if (!$organism) {
  1343. return array();
  1344. }
  1345. // don't show the browser if the settings in the admin page is turned off
  1346. // instead return the array indicating the status of the browser
  1347. $show_browser = variable_get('tripal_feature_browse_setting', 'show_feature_browser');
  1348. if (strcmp($show_browser, 'show_feature_browser')!=0) {
  1349. return array('enabled' => FALSE);
  1350. }
  1351. // get the list of available sequence ontology terms for which
  1352. // we will build drupal pages from features in chado. If a feature
  1353. // is not one of the specified typse we won't build a node for it.
  1354. $allowed_types = variable_get('chado_browser_feature_types', 'EST contig');
  1355. $allowed_types = preg_replace("/[\s\n\r]+/", " ", $allowed_types);
  1356. $so_terms = split(' ', $allowed_types);
  1357. // perform the query
  1358. $values = array(
  1359. 'organism_id' => $organism->organism_id,
  1360. 'type_id' => array(
  1361. 'name' => $so_terms
  1362. ),
  1363. );
  1364. $columns = array('feature_id', 'name', 'uniquename', 'type_id');
  1365. $options = array(
  1366. 'pager' => array('limit' => 10, 'element' => 0),
  1367. 'order_by' => array('name' => 'ASC'),
  1368. );
  1369. $features = tripal_core_chado_select('feature', $columns, $values, $options);
  1370. $pager = theme('pager');
  1371. // add the node ids and types
  1372. $nsql = "SELECT nid FROM {chado_feature} WHERE feature_id = %d";
  1373. $tsql = "SELECT name FROM {cvterm} WHERE cvterm_id = %d";
  1374. foreach ($features as $feature) {
  1375. $node = db_fetch_object(db_query($nsql, $feature->feature_id));
  1376. $type = db_fetch_object(chado_query($tsql, $feature->type_id));
  1377. $feature->nid = $node->nid;
  1378. $feature->type_name = $type->name;
  1379. }
  1380. return array( 'features' => $features, 'pager' => $pager, 'enabled' => TRUE );
  1381. }
  1382. /**
  1383. * This generates the Feature Browser which can optionally be included on library pages
  1384. * and shows all features belonging to the given library. This Browse can be shown/hidden
  1385. * on the Feature Configuration page.
  1386. *
  1387. * @ingroup tripal_feature
  1388. */
  1389. function tripal_feature_load_library_feature_browser($library) {
  1390. // don't show the browser if the settings in the admin page is turned off
  1391. // instead return the array indicating the status of the browser
  1392. $show_browser = variable_get('tripal_library_feature_browse_setting', 'show_feature_browser');
  1393. if (strcmp($show_browser, 'show_feature_browser')!=0) {
  1394. return array('enabled' => FALSE);
  1395. }
  1396. // get a list of feature types to include in the browser
  1397. $allowed_types = variable_get('chado_browser_feature_types', 'EST contig');
  1398. $allowed_types = preg_replace("/[\s\n\r]+/", " ", $allowed_types);
  1399. $so_terms = split(' ', $allowed_types);
  1400. $where_cvt = "";
  1401. foreach ($so_terms as $term) {
  1402. $where_cvt .= "CVT.name = '$term' OR ";
  1403. }
  1404. $where_cvt = drupal_substr($where_cvt, 0, drupal_strlen($where_cvt)-3); # strip trailing 'OR'
  1405. // get the features for this library
  1406. $sql = "SELECT F.name,F.feature_id,F.uniquename,CVT.name as cvname ".
  1407. "FROM {feature} F ".
  1408. " INNER JOIN {cvterm} CVT on F.type_id = CVT.cvterm_id ".
  1409. " INNER JOIN {library_feature} LF on F.feature_id = LF.feature_id ".
  1410. " INNER JOIN {library} L on LF.library_id = L.library_id ".
  1411. "WHERE LF.library_id = %d and ($where_cvt) ".
  1412. "ORDER BY feature_id ASC";
  1413. // the counting SQL
  1414. $csql = "SELECT count(*) ".
  1415. "FROM {feature} F".
  1416. " INNER JOIN {cvterm} CVT on F.type_id = CVT.cvterm_id ".
  1417. " INNER JOIN {library_feature} LF on F.feature_id = LF.feature_id ".
  1418. " INNER JOIN {library} L on LF.library_id = L.library_id ".
  1419. "WHERE LF.library_id = %d and ($where_cvt) ".
  1420. "GROUP BY L.library_id ";
  1421. $org_features = chado_pager_query($sql, 10, 0, $csql, $library->library_id);
  1422. $pager = theme('pager');
  1423. // prepare the query that will lookup node ids
  1424. $sql = "SELECT nid FROM {chado_feature} ".
  1425. "WHERE feature_id = %d";
  1426. $i=0;
  1427. $features = array();
  1428. while ($feature = db_fetch_object($org_features)) {
  1429. $node = db_fetch_object(db_query($sql, $feature->feature_id));
  1430. $feature->nid = $node->nid;
  1431. $features[$i++] = $feature;
  1432. }
  1433. return array( 'features' => $features, 'pager' => $pager, 'enabled' => TRUE );
  1434. }
  1435. /**
  1436. * This generates the Feature Browse which can optionally be included on library pages
  1437. * and shows all features belonging to the given library. This Browse can be shown/hidden
  1438. * on the Feature Configuration page.
  1439. *
  1440. * @ingroup tripal_feature
  1441. */
  1442. function tripal_feature_load_analysis_feature_browser($analysis) {
  1443. // don't show the browser if the settings in the admin page is turned off
  1444. // instead return the array indicating the status of the browser
  1445. $show_browser = variable_get('tripal_analysis_feature_browse_setting', 'show_feature_browser');
  1446. if (strcmp($show_browser, 'show_feature_browser')!=0) {
  1447. return array('enabled' => FALSE);
  1448. }
  1449. // get a list of feature types to include in the browser
  1450. $allowed_types = variable_get('chado_browser_feature_types', 'EST contig');
  1451. $allowed_types = preg_replace("/[\s\n\r]+/", " ", $allowed_types);
  1452. $so_terms = split(' ', $allowed_types);
  1453. $where_cvt = "";
  1454. foreach ($so_terms as $term) {
  1455. $where_cvt .= "CVT.name = '$term' OR ";
  1456. }
  1457. $where_cvt = drupal_substr($where_cvt, 0, drupal_strlen($where_cvt)-3); # strip trailing 'OR'
  1458. // get the features for this library
  1459. $sql = "SELECT F.name,F.feature_id,F.uniquename,CVT.name as cvname ".
  1460. "FROM {feature} F ".
  1461. " INNER JOIN {cvterm} CVT on F.type_id = CVT.cvterm_id ".
  1462. " INNER JOIN {analysisfeature} AF on F.feature_id = AF.feature_id ".
  1463. " INNER JOIN {analysis} A on AF.analysis_id = A.analysis_id ".
  1464. "WHERE A.analysis_id = %d and ($where_cvt) ".
  1465. "ORDER BY feature_id ASC";
  1466. // the counting SQL
  1467. $csql = "SELECT count(*) ".
  1468. "FROM {feature} F".
  1469. " INNER JOIN {cvterm} CVT on F.type_id = CVT.cvterm_id ".
  1470. " INNER JOIN {analysisfeature} AF on F.feature_id = AF.feature_id ".
  1471. " INNER JOIN {analysis} A on AF.analysis_id = A.analysis_id ".
  1472. "WHERE A.analysis_id = %d and ($where_cvt) ".
  1473. "GROUP BY A.analysis_id ";
  1474. $org_features = chado_pager_query($sql, 10, 0, $csql, $analysis->analysis_id);
  1475. $pager = theme('pager');
  1476. // prepare the query that will lookup node ids
  1477. $sql = "SELECT nid FROM {chado_feature} ".
  1478. "WHERE feature_id = %d";
  1479. $i=0;
  1480. $features = array();
  1481. while ($feature = db_fetch_object($org_features)) {
  1482. $node = db_fetch_object(db_query($sql, $feature->feature_id));
  1483. $feature->nid = $node->nid;
  1484. $features[$i++] = $feature;
  1485. }
  1486. return array( 'features' => $features, 'pager' => $pager, 'enabled' => TRUE );
  1487. }
  1488. /**
  1489. * used to sort the list of relationship objects by start position
  1490. *
  1491. * @ingroup tripal_feature
  1492. */
  1493. function tripal_feature_sort_rel_objects($a, $b) {
  1494. return strnatcmp($a->fmin, $b->fmin);
  1495. }
  1496. /**
  1497. * used to sort the list of relationship parts by start position
  1498. *
  1499. * @ingroup tripal_feature
  1500. */
  1501. function tripal_feature_sort_rel_parts_by_start($a, $b) {
  1502. foreach ($a as $type_name => $details) {
  1503. $astart = $a[$type_name]['start'];
  1504. break;
  1505. }
  1506. foreach ($b as $type_name => $details) {
  1507. $bstart = $b[$type_name]['start'];
  1508. break;
  1509. }
  1510. return strnatcmp($astart, $bstart);
  1511. }
  1512. /**
  1513. * used to sort the list of relationship parts by start position
  1514. *
  1515. * @ingroup tripal_feature
  1516. */
  1517. function tripal_feature_sort_rel_parts_by_end($a, $b) {
  1518. $val = strnatcmp($b['end'], $a['end']);
  1519. if ($val == 0) {
  1520. return strcmp($a['type'], $b['type']);
  1521. }
  1522. return $val;
  1523. }
  1524. /**
  1525. *
  1526. *
  1527. * @ingroup tripal_feature
  1528. */
  1529. function tripal_feature_color_sequence($sequence, $parts, $defline) {
  1530. $types = array();
  1531. // first get the list of types so we can create a color legend
  1532. foreach ($parts as $index => $t) {
  1533. foreach ($t as $type_name => $details) {
  1534. $types[$type_name] = 1;
  1535. }
  1536. }
  1537. $newseq .= "<div id=\"tripal_feature-featureloc_sequence-legend\">Legend: ";
  1538. foreach ($types as $type_name => $present) {
  1539. $newseq .= "<span id=\"tripal_feature-legend-$type_name\" class=\"tripal_feature-legend-item tripal_feature-featureloc_sequence-$type_name\" script=\"\">$type_name</span>";
  1540. }
  1541. $newseq .= "</div>Hold the cursor over a type above to highlight its positions in the sequence below. The colors in the sequence below merge when types overlap.";
  1542. // set the background color of the rows based on the type
  1543. $pos = 0;
  1544. $newseq .= "<pre id=\"tripal_feature-featureloc_sequence\">";
  1545. $newseq .= ">$defline\n";
  1546. // iterate through the parts. They should be in order.
  1547. $ends = array();
  1548. foreach ($parts as $index => $types) {
  1549. // get the start for this part. All types in this part start at the
  1550. // same position so we only need the first record
  1551. foreach ($types as $type => $child) {
  1552. $start = $child['start'];
  1553. break;
  1554. }
  1555. // add in the sequence up to the start of this part
  1556. for ($i = $pos; $i < $start; $i++) {
  1557. $newseq .= $sequence{$pos};
  1558. $seqcount++;
  1559. if ($seqcount % 50 == 0) {
  1560. $newseq .= "\n";
  1561. }
  1562. if (array_key_exists($pos, $ends)) {
  1563. foreach ($ends[$pos] as $end) {
  1564. $newseq .= "</span>";
  1565. }
  1566. }
  1567. $pos++;
  1568. }
  1569. // we want to sort the parts by their end. We want the span tag to
  1570. // to be added in the order the parts end.
  1571. usort($types, 'tripal_feature_sort_rel_parts_by_end');
  1572. // now add the child span for all types that start at this position
  1573. foreach ($types as $type) {
  1574. $class = "tripal_feature-featureloc_sequence-" . $type['type'];
  1575. $newseq .= "<span class=\"$class\">";
  1576. // add the end position
  1577. $end = $type['end'];
  1578. $ends[$end][] = $end;
  1579. }
  1580. }
  1581. // add in rest of the sequence
  1582. for ($i = $pos; $i <= strlen($sequence); $i++) {
  1583. $newseq .= $sequence{$pos};
  1584. $seqcount++;
  1585. if ($seqcount % 50 == 0) {
  1586. $newseq .= "\n";
  1587. }
  1588. if (array_key_exists($pos, $ends)) {
  1589. foreach ($ends[$pos] as $end) {
  1590. $newseq .= "</span>";
  1591. }
  1592. }
  1593. $pos++;
  1594. }
  1595. $newseq .= "</pre>";
  1596. return $newseq;
  1597. }
  1598. /**
  1599. * This function customizes the view of the chado_feature node. It allows
  1600. * us to generate the markup.
  1601. *
  1602. * @ingroup tripal_feature
  1603. */
  1604. function chado_feature_view($node, $teaser = FALSE, $page = FALSE) {
  1605. if (!$teaser) {
  1606. // use drupal's default node view:
  1607. $node = node_prepare($node, $teaser);
  1608. // if we're building the node for searching then
  1609. // we want to handle this within the module and
  1610. // not allow theme customization. We don't want to
  1611. // index all items (such as DNA sequence).
  1612. if ($node->build_mode == NODE_BUILD_SEARCH_INDEX) {
  1613. $node->content['index_version'] = array(
  1614. '#value' => theme('tripal_feature_search_index', $node),
  1615. '#weight' => 1,
  1616. );
  1617. }
  1618. elseif ($node->build_mode == NODE_BUILD_SEARCH_RESULT) {
  1619. $node->content['index_version'] = array(
  1620. '#value' => theme('tripal_feature_search_results', $node),
  1621. '#weight' => 1,
  1622. );
  1623. }
  1624. else {
  1625. // do nothing here, let the theme derived template handle display
  1626. }
  1627. }
  1628. return $node;
  1629. }
  1630. /**
  1631. * Display feature information for associated organisms. This function also
  1632. * provides contents for indexing
  1633. *
  1634. * @ingroup tripal_feature
  1635. */
  1636. function tripal_feature_nodeapi(&$node, $op, $teaser, $page) {
  1637. switch ($op) {
  1638. // Note that this function only adds feature view to an organism node.
  1639. // The view of a feature node is controled by the theme *.tpl file
  1640. case 'view':
  1641. switch ($node->type) {
  1642. case 'chado_organism':
  1643. // Show feature browser
  1644. $types_to_show = array('chado_organism', 'chado_library');
  1645. if (in_array($node->type, $types_to_show, TRUE)) {
  1646. $node->content['tripal_organism_feature_counts'] = array(
  1647. '#value' => theme('tripal_organism_feature_counts', $node),
  1648. );
  1649. $node->content['tripal_organism_feature_browser'] = array(
  1650. '#value' => theme('tripal_organism_feature_browser', $node),
  1651. );
  1652. }
  1653. break;
  1654. }
  1655. break;
  1656. }
  1657. }
  1658. /**
  1659. *
  1660. *
  1661. * @ingroup tripal_feature
  1662. */
  1663. function tripal_feature_preprocess_tripal_feature_relationships(&$variables) {
  1664. // we want to provide a new variable that contains the matched features.
  1665. $feature = $variables['node']->feature;
  1666. if (!$feature->all_relationships) {
  1667. $feature->all_relationships = tripal_feature_get_feature_relationships($feature);
  1668. }
  1669. }
  1670. /**
  1671. *
  1672. *
  1673. * @ingroup tripal_feature
  1674. */
  1675. function tripal_feature_preprocess_tripal_feature_alignments(&$variables) {
  1676. // we want to provide a new variable that contains the matched features.
  1677. $feature = $variables['node']->feature;
  1678. $feature = tripal_core_expand_chado_vars($feature, 'table', 'featureloc');
  1679. // get alignments as child
  1680. $cfeaturelocs = $feature->featureloc->feature_id;
  1681. if (!$cfeaturelocs) {
  1682. $cfeaturelocs = array();
  1683. }
  1684. elseif (!is_array($cfeaturelocs)) {
  1685. $cfeaturelocs = array($cfeaturelocs);
  1686. }
  1687. // get alignment as parent
  1688. $pfeaturelocs = $feature->featureloc->srcfeature_id;
  1689. if (!$pfeaturelocs) {
  1690. $pfeaturelocs = array();
  1691. }
  1692. elseif (!is_array($pfeaturelocs)) {
  1693. $pfeaturelocs = array($pfeaturelocs);
  1694. }
  1695. // get matched alignments (those with an itermediate 'match' or 'EST_match', etc
  1696. $mfeaturelocs = tripal_feature_get_matched_alignments($feature);
  1697. $feature->matched_featurelocs = tripal_feature_get_matched_alignments($feature);
  1698. // combine all three alignments into a single array for printing together in
  1699. // a single list
  1700. $alignments = array();
  1701. foreach ($pfeaturelocs as $featureloc) {
  1702. // if type is a 'match' then ignore it. We will handle those below
  1703. if (preg_match('/(^match$|^.*?_match|match_part)$/', $featureloc->feature_id->type_id->name)) {
  1704. continue;
  1705. }
  1706. $alignment = new stdClass();
  1707. $alignment->record = $featureloc;
  1708. $alignment->name = $featureloc->feature_id->name;
  1709. $alignment->nid = $featureloc->feature_id->nid;
  1710. $alignment->type = $featureloc->feature_id->type_id->name;
  1711. $alignment->fmin = $featureloc->fmin;
  1712. $alignment->fmax = $featureloc->fmax;
  1713. $alignment->phase = $featureloc->phase;
  1714. $alignment->strand = $featureloc->strand;
  1715. $alignments[] = $alignment;
  1716. }
  1717. foreach ($cfeaturelocs as $featureloc) {
  1718. // if type is a 'match' then ignore it. We will handle those below
  1719. if (preg_match('/(^match$|^.*?_match|match_part)$/', $featureloc->feature_id->type_id->name)) {
  1720. continue;
  1721. }
  1722. $alignment = new stdClass();
  1723. $alignment->record = $featureloc;
  1724. $alignment->name = $featureloc->srcfeature_id->name;
  1725. $alignment->nid = $featureloc->srcfeature_id->nid;
  1726. $alignment->type = $featureloc->srcfeature_id->type_id->name;
  1727. $alignment->fmin = $featureloc->fmin;
  1728. $alignment->is_fmin_partial = $featureloc->is_fmin_partial;
  1729. $alignment->fmax = $featureloc->fmax;
  1730. $alignment->is_fmax_partial = $featureloc->is_fmax_partial;
  1731. $alignment->phase = $featureloc->phase;
  1732. $alignment->strand = $featureloc->strand;
  1733. $alignments[] = $alignment;
  1734. }
  1735. // in matching features, the left feature is always the feature
  1736. // provided to this function.
  1737. foreach ($mfeaturelocs as $featureloc) {
  1738. // get more information about the right feature
  1739. $select = array('feature_id' => $featureloc->right_srcfeature_id);
  1740. $rfeature = tripal_core_generate_chado_var('feature', $select);
  1741. // now add to the list
  1742. $alignment = new stdClass();
  1743. $alignment->record = $featureloc;
  1744. $alignment->right_feature = $rfeature;
  1745. $alignment->name = $rfeature->name;
  1746. $alignment->nid = $rfeature->nid;
  1747. $alignment->type = $rfeature->type_id->name;
  1748. $alignment->fmin = $featureloc->left_fmin;
  1749. $alignment->is_fmin_partial = $featureloc->left_is_fmin_partial;
  1750. $alignment->fmax = $featureloc->left_fmax;
  1751. $alignment->is_fmax_partial = $featureloc->left_is_fmax_partial;
  1752. $alignment->phase = $featureloc->left_phase;
  1753. $alignment->strand = $featureloc->left_strand;
  1754. $alignment->right_fmin = $featureloc->right_fmin;
  1755. $alignment->right_is_fmin_partial = $featureloc->right_is_fmin_partial;
  1756. $alignment->right_fmax = $featureloc->right_fmax;
  1757. $alignment->right_is_fmax_partial = $featureloc->right_is_fmax_partial;
  1758. $alignment->right_phase = $featureloc->right_phase;
  1759. $alignment->right_strand = $featureloc->right_strand;
  1760. $alignments[] = $alignment;
  1761. }
  1762. $feature->all_featurelocs = $alignments;
  1763. }
  1764. /**
  1765. *
  1766. *
  1767. * @ingroup tripal_feature
  1768. */
  1769. function tripal_feature_preprocess_tripal_organism_feature_counts(&$variables) {
  1770. $organism = $variables['node']->organism;
  1771. $organism->feature_counts = tripal_feature_load_organism_feature_counts($organism);
  1772. }
  1773. /**
  1774. *
  1775. *
  1776. * @ingroup tripal_feature
  1777. */
  1778. function tripal_feature_preprocess_tripal_organism_feature_browser(&$variables) {
  1779. $organism = $variables['node']->organism;
  1780. $organism->feature_browser = tripal_feature_load_organism_feature_browser($organism);
  1781. }
  1782. /**
  1783. * Preprocessor function for the Library Feature Browser
  1784. *
  1785. * @ingroup tripal_feature
  1786. */
  1787. function tripal_feature_preprocess_tripal_library_feature_browser(&$variables) {
  1788. $library = $variables['node']->library;
  1789. $library->feature_browser = tripal_feature_load_library_feature_browser($library);
  1790. }
  1791. /**
  1792. * Preprocessor function for the Analysis Feature Browser
  1793. *
  1794. * @ingroup tripal_feature
  1795. */
  1796. function tripal_feature_preprocess_tripal_analysis_feature_browser(&$variables) {
  1797. $analysis = $variables['node']->analysis;
  1798. $analysis->feature_browser = tripal_feature_load_analysis_feature_browser($analysis);
  1799. }
  1800. /**
  1801. *
  1802. *
  1803. * @ingroup tripal_feature
  1804. */
  1805. function tripal_feature_cv_chart($chart_id) {
  1806. // we only want the chart to show feature types setup by the admin
  1807. $temp = rtrim(variable_get('tripal_feature_summary_report_mapping', ''));
  1808. $where = '';
  1809. if ($temp) {
  1810. $temp = explode("\n", $temp);
  1811. foreach ($temp as $key => $value) {
  1812. $temp2 = explode("=", $value);
  1813. $feature_type = rtrim($temp2[0]);
  1814. $where .= "CNT.feature_type = '$feature_type' OR \n";
  1815. }
  1816. if ($where) {
  1817. $where = drupal_substr($where, 0, -5); # remove OR from the end
  1818. $where = "($where) AND";
  1819. }
  1820. }
  1821. $organism_id = preg_replace("/^tripal_feature_cv_chart_(\d+)$/", "$1", $chart_id);
  1822. // The CV module will create the JSON array necessary for buillding a
  1823. // pie chart using jgChart and Google Charts. We have to pass to it
  1824. // a table that contains count information, tell it which column
  1825. // contains the cvterm_id and provide a filter for getting the
  1826. // results we want from the table.
  1827. $options = array(
  1828. count_mview => 'organism_feature_count',
  1829. cvterm_id_column => 'cvterm_id',
  1830. count_column => 'num_features',
  1831. size => '550x200',
  1832. filter => "$where CNT.organism_id = $organism_id",
  1833. );
  1834. return $options;
  1835. }
  1836. /**
  1837. *
  1838. *
  1839. * @ingroup tripal_feature
  1840. */
  1841. function tripal_feature_cv_tree($tree_id) {
  1842. // The CV module will create the JSON array necessary for buillding a
  1843. // pie chart using jgChart and Google Charts. We have to pass to it
  1844. // a table that contains count information, tell it which column
  1845. // contains the cvterm_id and provide a filter for getting the
  1846. // results we want from the table.
  1847. $organism_id = preg_replace("/^tripal_feature_cv_tree_(\d+)$/", "$1", $tree_id);
  1848. $options = array(
  1849. cv_id => tripal_cv_get_cv_id('sequence'),
  1850. count_mview => 'organism_feature_count',
  1851. cvterm_id_column => 'cvterm_id',
  1852. count_column => 'num_features',
  1853. filter => "CNT.organism_id = $organism_id",
  1854. label => 'Features',
  1855. );
  1856. return $options;
  1857. }
  1858. /**
  1859. *
  1860. *
  1861. * @ingroup tripal_feature
  1862. */
  1863. function tripal_feature_del_vocabulary() {
  1864. //include the file containing the required functions for adding taxonomy vocabs
  1865. module_load_include('inc', 'taxonomy', 'taxonomy.admin');
  1866. // get the vocabularies
  1867. $vocabularies = taxonomy_get_vocabularies();
  1868. // These taxonomic terms are hard coded because we
  1869. // know we have these relationships in the chado tables
  1870. // through foreign key relationships. The tripal
  1871. // modules that correspond to these chado "modules" don't
  1872. // need to be installed for the taxonomy to work.
  1873. foreach ($vocabularies as $vocab) {
  1874. if ($vocab->name == 'Feature Type') {
  1875. taxonomy_del_vocabulary($vocab->vid);
  1876. }
  1877. if ($vocab->name == 'Organism') {
  1878. taxonomy_del_vocabulary($vocab->vid);
  1879. }
  1880. if ($vocab->name == 'Library') {
  1881. taxonomy_del_vocabulary($vocab->vid);
  1882. }
  1883. if ($vocab->name == 'Analysis') {
  1884. taxonomy_del_vocabulary($vocab->vid);
  1885. }
  1886. }
  1887. }
  1888. /**
  1889. *
  1890. *
  1891. * @ingroup tripal_feature
  1892. */
  1893. function tripal_feature_return_fasta($feature, $desc) {
  1894. $fasta = ">" . variable_get('chado_feature_accession_prefix', 'ID') . "$feature->feature_id|$feature->name";
  1895. $fasta .= " $desc\n";
  1896. $fasta .= wordwrap($feature->residues, 50, "\n", TRUE);
  1897. $fasta .= "\n\n";
  1898. return $fasta;
  1899. }
  1900. /**
  1901. *
  1902. *
  1903. * @ingroup tripal_feature
  1904. */
  1905. function tripal_feature_job_describe_args($callback, $args) {
  1906. $new_args = array();
  1907. if ($callback == 'tripal_feature_load_fasta') {
  1908. $new_args['FASTA file'] = $args[0];
  1909. $organism = tripal_core_chado_select('organism', array('genus', 'species'), array('organism_id' => $args[1]));
  1910. $new_args['Organism'] = $organism[0]->genus . " " . $organism[0]->species;
  1911. $new_args['Sequence Type'] = $args[2];
  1912. $new_args['Name Match Type'] = $args[14];
  1913. $new_args['Name RE'] = $args[4];
  1914. $new_args['Unique Name RE'] = $args[5];
  1915. // add in the relationship arguments
  1916. $new_args['Relationship Type'] = $args[8];
  1917. $new_args['Relationship Parent RE'] = $args[9];
  1918. $new_args['Relationship Parent Type'] = $args[10];
  1919. // add in the database reference arguments
  1920. if ($args[7]) {
  1921. $db = tripal_core_chado_select('db', array('name'), array('db_id' => $args[7]));
  1922. }
  1923. $new_args['Database Reference'] = $db[0]->name;
  1924. $new_args['Accession RE'] = $args[6];
  1925. $new_args['Method'] = $args[11];
  1926. // add in the analysis
  1927. if ($args[13]) {
  1928. $analysis = tripal_core_chado_select('analysis', array('name'), array('analysis_id' => $args[13]));
  1929. }
  1930. $new_args['Analysis'] = $analysis[0]->name;
  1931. }
  1932. if ($callback == 'tripal_feature_delete_features') {
  1933. if ($args[0]) {
  1934. $organism = tripal_core_chado_select('organism', array('genus', 'species'), array('organism_id' => $args[0]));
  1935. $new_args['Organism'] = $organism[0]->genus . " " . $organism[0]->species;
  1936. }
  1937. else {
  1938. $new_args['Organism'] = '';
  1939. }
  1940. if ($args[1]) {
  1941. $analysis = tripal_core_chado_select('analysis', array('name'), array('analysis_id' => $args[1]));
  1942. $new_args['Analysis'] = $analysis[0]->name;
  1943. }
  1944. else {
  1945. $new_args['Analysis'] = '';
  1946. }
  1947. $new_args['Sequence Type'] = $args[2];
  1948. $new_args['Is Unique Name'] = $args[3];
  1949. $new_args['Features Names'] = $args[4];
  1950. }
  1951. elseif ($callback == 'tripal_feature_load_gff3') {
  1952. $new_args['GFF File'] = $args[0];
  1953. $organism = tripal_core_chado_select('organism', array('genus', 'species'), array('organism_id' => $args[1]));
  1954. $new_args['Organism'] = $organism[0]->genus . " " . $organism[0]->species;
  1955. $analysis = tripal_core_chado_select('analysis', array('name'), array('analysis_id' => $args[2]));
  1956. $new_args['Analysis'] = $analysis[0]->name;
  1957. $new_args['Use a Transaction'] = ($args[7] == 1) ? "Yes" : "No";
  1958. $new_args['Import only new features'] = ($args[3] == 1) ? "Yes" : "No";
  1959. $new_args['Import all and update'] = ($args[4] == 1) ? "Yes" : "No";
  1960. $new_args['Import all and replace'] = ($args[5] == 1) ? "Yes" : "No";
  1961. $new_args['Delete features'] = ($args[6] == 1) ? "Yes" : "No";
  1962. $target_organism = tripal_core_chado_select('organism', array('genus', 'species'), array('organism_id' => $args[8]));
  1963. $new_args['Target organism'] = $target_organism[0]->genus . " " . $target_organism[0]->species;
  1964. $new_args['Target type'] = $args[9];
  1965. $new_args['Create target'] = ($args[10] == 1) ? "Yes" : "No";
  1966. $new_args['Starting line'] = $args[11];
  1967. $new_args['Landmark Type'] = $args[12];
  1968. $new_args['Alternate ID attribute'] = $args[13];
  1969. $new_args['Create Organism'] = ($args[14] == 1) ? "Yes" : "No";
  1970. }
  1971. if ($callback == 'tripal_feature_sync_features') {
  1972. if ($args[0]) {
  1973. $organism = tripal_core_chado_select('organism', array('genus', 'species'), array('organism_id' => $args[0]));
  1974. $new_args['Organism'] = $organism[0]->genus . " " . $organism[0]->species;
  1975. }
  1976. else {
  1977. $new_args['Organism'] = '';
  1978. }
  1979. $new_args['Feature Types'] = $args[1];
  1980. }
  1981. return $new_args;
  1982. }
  1983. /**
  1984. * Implements hook_coder_ignore().
  1985. * Defines the path to the file (tripal_core.coder_ignores.txt) where ignore rules for coder are stored
  1986. */
  1987. function tripal_feature_coder_ignore() {
  1988. return array(
  1989. 'path' => drupal_get_path('module', 'tripal_feature'),
  1990. 'line prefix' => drupal_get_path('module', 'tripal_feature'),
  1991. );
  1992. }
  1993. /*
  1994. * Uses the value provided in the $id argument to find all features that match
  1995. * that ID by name, featurename or synonym. If it matches uniquenly to a single
  1996. * feature it will redirect to that feature page, otherwise, a list of matching
  1997. * features is shown.
  1998. */
  1999. function tripal_feature_match_features_page($id) {
  2000. $sql = "
  2001. SELECT
  2002. F.name, F.uniquename, F.feature_id,
  2003. O.genus, O.species, O.organism_id,
  2004. CVT.cvterm_id, CVT.name as type_name,
  2005. CF.nid,
  2006. array_agg(S.name) as synonyms
  2007. FROM {feature} F
  2008. INNER JOIN {organism} O on F.organism_id = O.organism_id
  2009. INNER JOIN {cvterm} CVT on CVT.cvterm_id = F.type_id
  2010. LEFT JOIN {feature_synonym} FS on FS.feature_id = F.feature_id
  2011. LEFT JOIN {synonym} S on S.synonym_id = FS.synonym_id
  2012. INNER JOIN public.chado_feature CF on CF.feature_id = F.feature_id
  2013. WHERE
  2014. F.uniquename = '%s' or
  2015. F.name = '%s' or
  2016. S.name = '%s'
  2017. GROUP BY F.name, F.uniquename, F.feature_id, O.genus, O.species,
  2018. O.organism_id, CVT.cvterm_id, CVT.name, CF.nid
  2019. ";
  2020. $results = chado_query($sql, $id, $id, $id);
  2021. $num_matches = 0;
  2022. // iterate through the matches and build the table for showing matches
  2023. $header = array('Uniquename', 'Name', 'Type', 'Species', 'Synonyms');
  2024. $rows = array();
  2025. $curr_match;
  2026. while ($match = db_fetch_object($results)) {
  2027. $curr_match = $match;
  2028. $synonyms = $match->synonyms;
  2029. $synonyms = preg_replace('/[\"\{\}]/', '', $synonyms);
  2030. $rows[] = array(
  2031. $match->uniquename,
  2032. "<a href=\"" . url("node/". $match->nid) ."\">" . $match->name . "</a>",
  2033. $match->type_name,
  2034. '<i>' . $match->genus . ' ' . $match->species . '</i>',
  2035. $synonyms,
  2036. );
  2037. $num_matches++;
  2038. }
  2039. // if we have more than one match then generate the table, otherwise, redirect
  2040. // to the matched feature
  2041. if ($num_matches == 1) {
  2042. drupal_goto(url("node/" . $curr_match->nid));
  2043. }
  2044. if ($num_matches == 0) {
  2045. return "<p>No features matched the given name '$id'</p>";
  2046. }
  2047. $table_attrs = array(
  2048. 'class' => 'tripal-table tripal-table-horz'
  2049. );
  2050. $output = "<p>The following features match the name '$id'.</p>";
  2051. $output .= theme_table($header, $rows, $table_attrs, $caption);
  2052. return $output;
  2053. }
  2054. /**
  2055. *
  2056. * @param unknown_type $form
  2057. * @param unknown_type $form_state
  2058. * @param unknown_type $form_id
  2059. */
  2060. function tripal_feature_form_alter(&$form, &$form_state, $form_id) {
  2061. if ($form_id == "tripal_feature_seq_extract_form") {
  2062. // updating the form through the ahah callback sets the action of
  2063. // the form to the ahah callback URL. We need to set it back
  2064. // to the normal form URL
  2065. $form['#action'] = url("find/sequences");
  2066. }
  2067. }